Truth in a fair fight: Eli Rabett explains Gates Foundation’s good work against malaria

September 21, 2010

Good works are oft’ interred with the bones of the good workers, according to that Brutus Mark Antony guy — and at Watts Up With That, many work to bury any good workers, too.

So, a specially-scrubbed carrot is due Eli Rabett, who details the good works of the Gates Foundation against malaria, just to counteract the clamor of the howling at WUWT.

. . . since this started with an attack on Bill Gates, it is important to understand at least some of the interesting things that the Gates Foundation is doing to help fight malaria.

Among these, Affordable Medicines for Malaria (AMFM), is one of the cleverest, and may even work. The idea is that AMFM will buy ACT (artemisinin combination therapy – something else the Wattoids didn’t know about) drugs directly from the manufacturers in huge amounts at deep discount, and pass the drugs on to the distributors, public health agencies, private wholesale pharmacies, and NGOs at so far below cost that even counterfeit drugs cost more. The private wholesalers can take their profit.

One may hope someone will find the magic bullet to fight malaria.  There’s the Ghost of Santayana pacing the chalkboard again, however:  Our experience shows that magic is not real, no magic bullet has ever existed against malaria, and DDT is not now the magic bullet it never was in the first place.  “Those who cannot remember the past are condemned to repeat it,” Ghost of Santayana mutters.

A special place in hell is reserved for those who remember the past, but tell false tales about it instead.


Still evil and wrong: McIlhinney still leads a cover up of malaria facts

September 20, 2010

U.S. President’s Malaria Initiative (PMI) Africa Indoor Residual Spraying (AIRS) Project found this warehouse with 119 tons of leftover, surplus and expired DDT in Ethiopia. In total, PMI AIRS Progect found 930 tons of unused DDT in Ethiopia, in 1,600 tons of expired pesticides total. Other nations have other surplus DDT stocks. Africa never suffered a shortage of DDT.

U.S. President’s Malaria Initiative (PMI) Africa Indoor Residual Spraying (AIRS) Project found this warehouse with 119 tons of leftover, surplus and expired DDT in Ethiopia. In total, PMI AIRS Progect found 930 tons of unused DDT in Ethiopia, in 1,600 tons of expired pesticides total. Other nations have other surplus DDT stocks. Africa never suffered a shortage of DDT.

Watch the video, and you can see God trying to stop her from talking, putting that frog in her throat.

Ann McIlhinney was wrong when she made the movie “Not Evil, Just Wrong,” and she’s still spreading false tales.  I found her diatribe, interestingly enough at a site called 2012 Doomsday Predictions.

I only respond to the first six minutes or so — you get the idea.  McIlhinney leaves no falsehood untold, no crazy charge not leveled at Rachel Carson and “environmentalists.”

Here’s the film clip of McIlhinney misleading the masses:

Here is my quick and dirty response:

1. Environmentalists are not calling for a ban on coal, oil or gas. Fear talk. Why would anyone tell such a whopping lie? How do we know the film lies? Who is this “environmentalist” they fear to name?

2. Rachel Carson was right — DDT kills ecosystems. Carson said we needed to restrict the use of DDT in order to keep it viable as a pesticide. But few listened (not McIlhinney, that’s for sure). Consequently, DDT became ineffective against mosquitoes that carry malaria, scuttling the World Health Organization’s ambitious campaign to eradicate malaria. Had that not happened, and had we eradicated malaria by 1975 as planned, millions of lives could have been saved. McIlhinney is the one with blood on her hands.

3. DDT has never been banned worldwide, was never banned in Africa, and is still used in those places it still works, under a special treaty signed in 2001. McIlhinney hopes you won’t know about that treaty, and fails to mention it herself. What’s she trying to hide?

4. Carson did not say DDT was the sole culprit for the decline of birds — but by 1962, it was the sole culprit preventing their recovery. Bald eagles and brown pelicans have come off the endangered species list, populations recovering in almost lock-step with the decline of DDT in the birds’ flesh — proof that Carson was right.

5. Under U.S. law, no agency could ban a useful pesticide without mountains of evidence that the pesticide was dangerous. Four separate court proceedings looked at DDT, two before the EPA acted, and two appeals after EPA banned DDT use on crops. All four courts found DDT to be dangerous and uncontrollable in the wild. The two appeals of EPA’s labeling change were both decided on summary judgment — the science was so powerfully on Carson’s side. In May 1963 the President’s Science Advisory Council reported on their fact checking of Carson’s book — they said Carson was dead right in everything but one: Carson was too easy on DDT. That panel, with its significant population of Nobel winners, called for quick action against DDT. Why doesn’t McIlhinney give the facts here?

6. The claim that EPA’s ban influenced WHO is pure bullfeathers. WHO had to end its malaria eradication campaign, using DDT, in 1965 — the mosquitoes were immune to the stuff. EPA didn’t act until seven years later, and EPA’s jurisdiction extends only to the borders of the U.S. In fact, EPA’s “ban” left DDT to be manufactured in the U.S. for export to Africa. Can’t McIlhinney read a calendar? The “ban” in 1972 did not travel back through time to stop WHO from using DDT. (For that matter, WHO never completely stopped DDT — wherever it could work, they used it, and still do.)

7. DDT has always been available for any government in Africa to use. What that guy in the film is really saying is racist: He’s claiming Africans were too stupid to use DDT, though it was cheap and available, and though it would save their lives. Don’t listen to him. Africans are not stupid: They’d use DDT were it effective and safe. Shame on McIlhinney for entertaining such a claim.

8. Malaria did not skyrocket after DDT was banned in the U.S. Mosquitoes don’t migrate that far. There was an uptick in malaria 20 years later, when the pharmaceuticals that cure malaria in humans, ceased to be effective.

But today, malaria rates are the lowest they’ve been in recorded history, and malaria death rates are the lowest they’ve been in human history. When the U.S. banned DDT spraying on cotton in 1972, about 2 million people a year died from malaria. Today, the death toll is under 900,000. Don’t be frightened or stampeded by erroneous, large figures.

In the end, we can’t poison Africa to health, and if we could, it would be immoral to do that instead of building health care to fight diseases.

Children die because hard-hearted politicos like Ann McIlhinney frustrate the work of malaria fighters, and mislead policy makers away from solutions that would save children’s lives.

Shame on her.


Do bednets make a difference?

September 4, 2010

Go see these two Associated Press photos from Pakistan, at MSNBC’s site — same location, same day.


Annals of DDT: 880,000 died from malaria in 2008

August 26, 2010

Once upon a time I easily found a chart from the World Health Organization (WHO) which provided a year-by-year tally of malaria deaths, worldwide, from the 1940s to the present.

Of course, now that I need that chart to note that malaria deaths are much lower today than they were when DDT was overused generally and sometimes misused in the fight against malaria, I can’t find it.  So, we’ll take the figures where we can find them.

In 2008, worldwide there were over 880,000 deaths from malaria.  This is significantly lower than the usual claim of “millions of deaths each year.”  We can find this figure in a document from the Global Environmental Facility (GEF), the organization that organizes the work of 182 nations to work for solutions to environmental problems, including fighting malaria, in a report on the 2009 meeting of the Stockholm Convention focused on fighting malaria,  “Countries move toward more sustainable ways to roll back malaria.”

However concern over DDT is matched by concern over the global malaria burden in which close to 250 million cases a year result in over 880 000 deaths. Thus any reduction in the use of DDT or other residual pesticides must ensure the level of transmission interruption is, at least, maintained.

Numbers here may be estimates not updated from current-year records.  The figure “over 880,000 deaths” looks and sounds awfully close to numbers reported in 2006, as you can see in this report from the Kaiser Family Foundation on U.S. global health policies:

Number of Annual Malaria Cases Worldwide Decreases, Disease Still Remains a Challenge, WHO’s World Malaria Report 2008 Says

Thursday, September 18, 2008

There were about 247 million malaria cases worldwide in 2006, according to the World Malaria Report 2008, which was released by the World Health Organization on Thursday, Reuters reports (MacInnis, Reuters, 9/18). According to the report, 3.3 billion people worldwide were at risk for malaria in 2006, and the disease remains a major burden among children younger than age five and in many African countries (AFP/Google.com, 9/18).

The report included reduced estimates of the global malaria burden that were calculated with new surveillance measures for non-African countries. The estimate of 247 million malaria cases is lower than the estimated 350 million to 500 million annual malaria cases reported in WHO’s World Malaria Report 2005. The new report estimated there were 881,000 malaria deaths in 2006, down from the previous estimate of one million deaths. The reduced figures are the result of new calculation methods, and it is unknown whether malaria cases and deaths actually declined from 2004 to 2006, WHO said (Reuters, 9/18). Although malaria control efforts have helped reduce the global malaria burden, most malaria-endemic countries are not meeting WHO targets for malaria control, the report said, noting that there is “no evidence yet to show that malaria elimination can be achieved and maintained in areas that currently have high transmission” (Bennett/Doherty, Bloomberg, 9/18).

WHO attributed the revised malaria estimates to new assessment measures in Asia, where data used for the 2005 report had not been updated for 40 years. According to Mac Otten — coordinator of surveillance, monitoring and evaluation at WHO’s Global Malaria Program — factors such as deforestation, urbanization and malaria control efforts have affected malaria estimates in Asia (Blue, Time, 9/17). Cambodia, Laos, the Philippines, Thailand and Vietnam all reported a decline in malaria deaths in 2006 (Bloomberg, 9/18).

WHO’s surveillance methods in Africa, which estimate malaria prevalence by using climate data and sample surveys, have remained the same since the 2005 report, the report said (Reuters, 9/18). According to the report, 45 of the 109 malaria-endemic countries worldwide are in Africa, and more than half of the continent’s malaria cases in 2006 occurred in the Democratic Republic of Congo, Ethiopia, Kenya, Nigeria and Tanzania (AFP/Google.com, 9/18). The report noted that malaria interventions have helped reduce malaria cases and deaths by more than 50% in Eritrea, Rwanda, Sao Tome and Principe, and the Tanzanian island of Zanzibar (Time, 9/17).The report found that about 40% of people at risk for malaria in Africa had access to insecticide-treated nets last year, compared with 3% in 2001 (Bloomberg, 9/18). The report also found that the number of ITNs distributed to national malaria control programs was enough to cover 26% of people in 37 African countries but that most African countries did not meet WHO’s target of 80% coverage for the four main malaria treatments: ITNs, artemisinin-based combination therapies, indoor-insecticide spraying programs and treatment for pregnant women (AFP/Google.com, 9/18).

Note also that this total of 880,000 is more than the previously reported 863,000.  Hmmm.


DDT and birth defects: South African television asks questions

July 23, 2010

Steven Milloy, Roger Bate, and Richard Tren hope you never see this television production — they hope you never even hear about it.  It’s one more indication that Rachel Carson was right.

They hope you never even hear about it.  It’s set for telecast in South Africa next Tuesday:

Special Assignment to broadcast episode on ‘Collateral Damage’

Published: 22 July 2010

This week, Special Assignment looks at those affected by the dangerous DDT chemical and also those who say it is a necessary evil to prevent many South Africans from dying.

“I have problems with my balls,” says ‘George’. “I was born without testicles,” adds ‘Joseph’, yet another man born in the Limpopo area. These two and many other young men in Venda share a common story.

Each year, South Africa sprays more than 90 tonnes of the toxic DDT chemical in homesteads in KwaZulu-Natal and Limpopo areas. Though DDT, a persistent organic chemical which can remain in the environment for as much as 40 years is banned across the world, South Africa still uses it to control malaria in the country. Recent studies have however showed that DDT is harmful to humans with hundreds of kids born in the Venda area showing signs of genital deformities. The chemical has also been associated with breast cancer; diabetes; and spontaneous abortion. Yet it remains South Africa’s best option for the prevention of malaria which kills millions of people each year across Africa. This week, Special Assignment looks at those affected by this chemical and also those who say it is a necessary evil to prevent many other South Africans from dying.

‘Collateral Damage’ will be broadcast on Special Assignment on Tuesday, 27 July, at 20:31 on SABC3.


University of Arizona’s “malaria-proof” mosquito

July 15, 2010

This could be good news:  A genetically-altered mosquito that doesn’t harbor the malaria parasite, and so cannot pass it along to humans it bites in its later life.

One more way to end the use and production of DDT.

Press release from the University of Arizona (one of my alma mater schools):

The first malaria-proof mosquito

Scientists at the University of Arizona have achieved a breakthrough in the fight against malaria: a mosquito that can no longer give the disease to humans

IMAGE: Michael Riehle, holding genetically altered mosquitoes, and his team work in a highly secure lab environment to prevent genetically altered mosquitoes from escaping.

Click here for more information.

For years, researchers worldwide have attempted to create genetically altered mosquitoes that cannot infect humans with malaria. Those efforts fell short because the mosquitoes still were capable of transmitting the disease-causing pathogen, only in lower numbers.

Now for the first time, University of Arizona entomologists have succeeded in genetically altering mosquitoes in a way that renders them completely immune to the parasite, a single-celled organism called Plasmodium. Someday researchers hope to replace wild mosquitoes with lab-bred populations unable to act as vectors, i.e. transmit the malaria-causing parasite.

“If you want to effectively stop the spreading of the malaria parasite, you need mosquitoes that are no less than 100 percent resistant to it. If a single parasite slips through and infects a human, the whole approach will be doomed to fail,” said Michael Riehle, who led the research effort, the results of which will be published July 15 in the journal Public Library of Science Pathogens. Riehle is a professor of entomology in the UA’s College of Agriculture and Life Sciences and is a member of the BIO5 Institute.

Riehle’s team used molecular biology techniques to design a piece of genetic information capable of inserting itself into a mosquito’s genome. This construct was then injected into the eggs of the mosquitoes. The emerging generation carries the altered genetic information and passes it on to future generations. For their experiments, the scientists used Anopheles stephensi, a mosquito species that is an important malaria vector throughout the Indian subcontinent.

The researchers targeted one of the many biochemical pathways inside the mosquito’s cells. Specifically, they engineered a piece of genetic code acting as a molecular switch in the complex control of metabolic functions inside the cell. The genetic construct acts like a switch that is always set to “on,” leading to the permanent activity of a signaling enzyme called Akt. Akt functions as a messenger molecule in several metabolic functions, including larval development, immune response and lifespan.

When Riehle and his co-workers studied the genetically modified mosquitoes after feeding them malaria-infested blood, they noticed that the Plasmodium parasites did not infect a single study animal.

IMAGE: Under UV light, this mosquito larva reveals a red fluorescent marker in its nervous system, causing eyes and nerves to glow. The marker’s presence tells the researchers in Riehle’s…

Click here for more information.

“We were surprised how well this works,” said Riehle. “We were just hoping to see some effect on the mosquitoes’ growth rate, lifespan or their susceptibility to the parasite, but it was great to see that our construct blocked the infection process completely.”

Of the estimated 250 million people who contract malaria each year, 1 million – mostly children – do not survive. Ninety percent of the number of fatalities, which Riehle suspects to be underreported, occur in Sub-Saharan Africa.

Each new malaria case starts with a bite from a vector – a mosquito belonging to the genus Anopheles. About 25 species of Anopheles are significant vectors of the disease.

Only the female Anopheles mosquitoes feed on blood, which they need to produce eggs. When they bite an infected human or animal, they ingest the malaria parasite.

Once the Plasmodium cells find themselves in the insect’s midgut, they spring into action. They leave the insect’s digestive tract by squeezing through the midgut lining. The vast majority of Plasmodium cells do not survive this journey and are eliminated by the mosquito’s immune cells. A tiny fraction of parasite cells, usually not more than a handful, make it and attach themselves on the outside of the midgut wall where they develop into brooding cells called oocysts.

Within 10-12 days, thousands of new Plasmodium cells, so-called sporozoites, sprout inside the oocyst. After hatching from the oocyst, the sporozoites make their way into the insect’s salivary glands where they lie in wait until the mosquito finds a victim for a blood meal. When the mosquito bites, some sporozoites are flushed into the victim’s bloodstream.

“The average mosquito transmits about 40 sporozoites when it bites,” said Riehle, “but it takes only one to infect a human and make a new malaria victim.”

Several species of Plasmodium exist in different parts of the world, all of which are microscopically small single-celled organisms that live in their hosts’ red blood cells. Each time the parasites undergo a round of multiplication, their host cells burst and release the progeny into the bloodstream, causing the painful bouts of fever that malaria is known and feared for.

Malaria killed more soldiers in the Civil War than the fighting, according to Riehle. In fact, malaria was prevalent in most parts of the U.S. until the late 1940s and early 1950, when DDT spraying campaigns wiped the vectors off the map. Today, a new case of malaria occurs in the U.S. only on rare occasions.

The severity of the disease depends very largely on the species of the Plasmodium parasite the patient happens to contract.

“Only two species of Plasmodium cause the dreaded relapses of the disease,” said Riehle. “One of them, Plasmodium vivax, can lie dormant in the liver for 10 to 15 years, but now drugs have become available that target the parasites in the liver as well as those in the blood cells.”

That said, there are no effective or approved malaria vaccines. A few vaccine candidates have gone to clinical trials but they were shown to either be ineffective or provide only short-term protection. If an effective vaccine were to be developed, distribution would be a major problem, Riehle said.

Researchers and health officials put higher hopes into eradication programs, which aim at the disease-transmitting mosquitoes rather than the pathogens that cause it.

“The question is ‘What can we do to turn a good vector into a bad vector?'” Riehle said.

“The eradication scenario requires three things: A gene that disrupts the development of the parasite inside the mosquito, a genetic technique to bring that gene into the mosquito genome and a mechanism that gives the modified mosquito an edge over the natural populations so they can displace them over time.”

“The third requirement is going to be the most difficult of the three to realize,” he added, which is why his team decided to tackle the other two first.

“It was known that the Akt enzyme is involved in the mosquito’s growth rate and immune response, among other things,” Riehle said. “So we went ahead with this genetic construct to see if we can ramp up Akt function and help the insects’ immune system fight off the malaria parasite.”

The second rationale behind this approach was to use Akt signaling to stunt the mosquitoes’ growth and cut down on its lifespan.

“In the wild, a mosquito lives for an average of two weeks,” Riehle explained. “Only the oldest mosquitoes are able to transmit the parasite. If we can reduce the lifespan of the mosquitoes, we can reduce the number of infections.”

His research team discovered that mosquitoes carrying two copies of the altered gene had lost their ability to act as malaria vectors altogether.

“In that group of mosquitoes, not a single Plasmodium oocyst managed to form.”

At this point, the modified mosquitoes exist in a highly secured lab environment with no chance of escape. Once researchers find a way to replace wild mosquito populations with lab-bred ones, breakthroughs like the one achieved by Riehle’s group could pave the way toward a world in which malaria is all but history.

###

This study was funded by the National Institutes of Health.

Reference: Corby-Harris et al. Activation of Akt Signaling Reduces the Prevalence and Intensity of Malaria Parasite Infection and Lifespan in Anopheles stephensi Mosquitoes. Public Library of Science (PLoS) Pathogens, July 2010 issue: www.plospathogens.org

How do you like them genetic engineering guys now?


Africa Fighting Malaria claims to be fighting malaria

July 6, 2010

In response to earlier analysis here, that Africa Fighting Malaria (AFM) does not appear to do much to fight malaria, Richard Tren wrote a comment to a post at TropIKA.

Tren is unlikely to respond here; I gather he does not want to answer questions.

I will comment more completely later — I’m still not sure just what AFM does to fight malaria.  It’s humorous that he calls my question an “ad hominem” attack; I ask the questions because Tren has led the fight in the unholy smear campaign against Rachel Carson, against the U.S. Fish and Wildlife Service, against dozens of other scientists and science itself, against saving the bald eagle, against wise use of pesticides, against bed nets, against fighting malaria other than poisoning Africa. Most recently, as Tren mentions, he published a book that repeats much of the inaccurate claims and hoaxes he has relied on before.  But he’s concerned about attacks on him personally, and not the substance.

Why am I concerned at all?  The AFM-led assault on the World Health Organization, Rachel Carson, malaria fighters in public health, scientists and environmentalists  has come at an extremely high cost in human life. It is impossible to know how many people have died needlessly from malaria, yellow fever, leishmaniasis, dengue fever and other insect-borne diseases in the absence of medical care or prevention programs in lieu of DDT, but it must be millions — many of them could have been saved but for policy-makers’ beliefs that an increase in DDT could poison these people to health quickly and cheaply.  The campaign in favor of DDT has hampered serious efforts to fight malaria especially, such as Nothing But Nets and USAID’s support for prophylactic measures to beat the disease.

Does Tren answer the question well, what does AFM actually do to fight malaria?

Help me find some substance here in Tren’s letter (unedited by me in any way):

Paul,

It’s hard to know whether or not to respond to this. To say that we are ‘under fire’ because of the sniping and ad-hominem attacks from a blogger who has, for some or other reason, decided to take issue with my organization is an exaggeration to say the least. However even though your post has so far received zero comments I’d like to make a few things clear for the record.

AFM was founded in South Africa in 2000 and we opened an office in the United States in 2003. We maintain an office and a presence in South Africa as well as an office in the Washington DC. You say that we have focused most of our attention on one issue – the desirability of using DDT in mosquito control programs. Actually we focus on malaria control programs, not mosquito control programs; but to an extent you are correct. We have focused on this issue because DDT continues to play an important role in malaria control in many southern African programs (and in some other countries) and over the years other countries, such as Uganda have attempted to use DDT but have been harshly criticized and domestic and international groups forcing DDT spraying programs to close down. AFM defends DDT because of its outstanding record in saving lives and because it is under attack. The scare stories and smear campaigns against this insecticide are so pervasive and the misunderstanding about it so widespread that it is vital for some group or individual to provide a counterbalance, based on sound science.

AFM was a critical voice in securing an exemption for the use of DDT in the Stockholm Convention, and our research and advocacy work helped to usher in far-reaching reforms to US support for malaria control. We recently published a major book on DDT and its role in malaria control – The Excellent Powder – see http://www.excellentpowder.org. Additionally, we have responded to several recent publications that seek to limit the use of DDT (and interestingly other insecticides such as pyrethroids), with letters in Environmental Health Perspectives, British Journal of Urology International and working papers published on our own website. We have publicly exposed and criticized the way in which anti-insecticide advocacy groups, like Pesticide Action Network, have lobbied against indoor residual spraying programs that are funded and maintained by the President’s Malaria Initiative (PMI). All of these letters and papers can be accessed from our website – if any of your readers have any difficulty in accessing them, I’d be happy to forward them.

A word on our critical review of a paper published in British Journal of Urology International. Several researchers from the University of Pretoria published a paper in late 2009 claiming that DDT use in IRS would increase the chance that a boy would be born with a urogenital birth defect by around 33%. This paper was widely covered in the media and caused considerable problems for the malaria control programs in southern Africa. One scientist in particular even claimed on a public TV program that DDT was linked to the case of intersex South African athlete, Caster Semenya; this was further promoted in the print media causing great concern among people living in malaria areas. As we documented in our review, the research paper was very deeply flawed and the conclusions of the authors were premature to say the least. Although it required a considerable investment of time and effort, we respond with a formal review of both the paper and the outrageous claims made in the media for which there was no scientific evidence. Our letter to the journal, which was co-authored by some senior malaria scientists from South Africa, was published in the journal. Although the authors of the paper were given ample opportunity to respond to our criticisms, they declined – which is telling.

You make the point that we have focused on DDT – true, we have done so because there is a need for someone to respond to the never-ending claims of harm. Someone has to stand up and defend the malaria control programs that are using DDT and implementing effective malaria control measures – perhaps if some of the other advocacy groups or individuals stepped up and helped to defend IRS and the use of public health insecticides, we wouldn’t have to spend so much of our time and energy doing it.

In addition to defending the use of public health insecticides, we strongly advocate for investments in new insecticides and against regulations and policies that may hamper access to insecticides or investment in new insecticides. For instance in 2008/9 we coordinated a response to proposed EU regulation of insecticides that could limit access to insecticides. (The various documents that I describe are available on our website) As an example of our work in this regard, we recently held a successful policy briefing on Capitol Hill (in Washington, D.C.) involving stakeholders from advocacy groups, donor agencies and the private sector. Again details of this are available on our website.

Aside from our advocacy and defense of public health insecticides, we have been successful in exposing the ongoing use of sub-standard malaria medicines as well as fake medicines in Africa. Our research studies have been published in Malaria Journal, PLoS One, and other journals. In order to maintain this project and to get safe and effective malaria medicines out to communities we have raised funds for malaria treatments and have focused on increasing access in Uganda. Again, details are available on our website.

Lastly AFM is involved in a research and advocacy program to remove import tariffs and non-tariff barriers from malaria commodities. As malaria programs are scaled up, it is increasingly important to ensure that barriers to access are removed – import tariffs and non-tariff barriers can be significant and AFM is very excited to be involved in this important area of research and advocacy. See http://www.m-tap.org for more details.

So, I hope that this helps to answer the questions about what we do. We are a policy and research group, we have never pretended to be anything else and our track record stands for itself.

Paul, if you want to have a discussion about our work, I’d be happy to correspond with you and your colleagues on a basis of cordiality and respect. I would be delighted to debate our work on DDT, public health insecticides, drug quality and import tariffs and non-tariff barriers, but let’s leave the sniping bloggers and their misleading and biased comments out of this.

Richard Tren


Malaria tough to beat: Canadian Press review of The Fever

July 5, 2010

At Canadian Press, Carl Hartman reviewed The Fever: How Malaria Has Ruled Humankind for 500,000 Years, a dramatic work of non-fiction about malaria and mosquitoes by Sonia Shah (Sarah Crichton Books/Farrar, Straus and Giroux 2010).  Hartman concluded:

Evidence of mosquito resistance to the drug has been recently reported.

Shah is skeptical of a surge of private charity that emphasizes the use of mosquito nets following the decline of government-led anti-malaria programs in the 1990s. Acknowledging the contributions of Bill Gates and former Presidents George W. Bush and Bill Clinton, she lists Veto the ‘Squito, a youth-led charity; Nothing but Nets, an anti-malarial basketball charity; and World Swim Against Malaria. She quotes The New York Times as decrying “hip ways to show you care.”

Her own comment: “Just because something is simple doesn’t necessarily mean that people will do it.”

“(T)he schools, roads, clinics, secure housing and good governance that enable regular prevention and prompt treatment must be built,” she concludes. “Otherwise the cycle of depression and resurgence will begin anew; malaria will win, as it always has.”

Anti-environmentalists, anti-scientists, and other conservatives won’t like the book:  It says we can’t beat malaria cheaply by just spreading a lot of poison on Africa and Africans.

Especially if you’re doing the noble thing and vacationing in the Gulf of Mexico in Alabama, or Mississippi, or Louisiana, you may want to read this.  If you’re vacationing in the Hamptons, Martha’s Vinyard, or Cannes, buy several copies to pass out at dinner with your friends.

More:


French researchers find link between DDT exposure and Parkinson’s Disease

June 16, 2010

French researchers looked at men who possess a gene that predisposes them to Parkinson’s Disease, and found that DDT exposure correlates with actual onset of the disease.

(Reuters) – Men with certain genetic variations who were exposed to some toxic pesticides which are now largely banned run an increased risk of developing Parkinson’s disease, French scientists said Monday.

Researchers found that among men exposed to pesticides such as DDT, carriers of the gene variants were three and a half times more likely to develop Parkinson’s than those with the normal version of the gene.

The scientists, whose work was published in the Archives of Neurology journal, think the brains of people with the gene variant fail to flush out toxins as efficiently as those with normal versions of the gene, suggesting environmental as well as genetic factors are important in the risk of Parkinson’s.

DDT, which belongs to a group of pesticides known as organochlorines, is one of the “Dirty Dozen” chemicals banned by a 2001 United Nations convention after it was found to be a toxin that can suppress the immune system.

It is infamous for threatening bird populations by thinning eggshells, and has also been linked to increase risks in humans of diseases such as cancer and Parkinson’s — an incurable and often deadly brain disease.

But exemptions to the DDT ban are allowed in many developing nations because it so effective in killing mosquitoes. DDT’s Swiss inventor Paul Hermann Muller won the 1948 Nobel Prize for Medicine — before its wider toxic effects were known.

Alexis Elbaz and Fabien Dutheil, of France’s National Institute for Health and Medical Research (INSERM) studied 101 men with Parkinson’s and 234 without the disease to look at links between organochlorine exposure and Parkinson’s disease.

The study included only men, and all of them had had high levels of exposure to pesticides through their work as farmers.

The scientists found the link was around 3.5 times stronger in men who carried two copies of a gene known as ABCB1, which plays a role in helping the brain flush out dangerous chemicals.

File that one away for the next time some yahoo claims there are no harmful effects to health from DDT.  The study probably could not distinguish between heavy exposure to pesticides and the much lighter exposure assumed to result from Indoor Residual Spraying of DDT, such as is used in some places in Africa in the fight against malaria.

Anybody got a copy of the actual study, in English?


Fighting malaria: Bed nets crucial

June 12, 2010

Nota bene:  DDT not labeled “crucial”


Does Africa Fighting Malaria actually fight malaria?

June 11, 2010

This spring’s publication of a book, The Excellent Powder, by Richard Tren and Donald Roberts, repeating most of the false claims about malaria and DDT, got me wondering. Their organization, Africa Fighting Malaria (AFM):

Does AFM do anything to fight malaria? At its own website it makes some astoundingly grandiose claims:

In its seven years of operation, AFM has helped transform malaria control by taking on and turning around failing public health institutions, donor agencies and governments.

Offhand I can’t think of any public health institution AFM has even been involved with, other than its undeserved criticism of the World Health Organization — and if anyone knows of any donor agency or government AFM has “turned around,” the history books await your telling the story.

Africa Fighting Malaria springs to life every year around World Malaria Day, April 25, with editorials claiming environmentalists have killed millions. AFM seems to be one of the sources of the bizarre and false claim that Rachel Carson is a “mass murderer.” AFM makes noise whenever there is difficulty getting a DDT spraying campaign underway in any part of Africa, for any reason, quick to lay the blame on environmentalists, even though the blame generally rests in other places. AFM is quick on the draw to try to discredit all research into DDT that suggests it poses any health threat, though so far as I can tell AFM has published no counter research, nor has it conducted any research of its own.

In its 2009 Annual Report, AFM proudly states “AFM is the only advocacy group that routinely supports IRS [Indoor Residual Spraying] and through its advocacy work defends the use of DDT for malaria control.”

Cleverly, and tellingly, they do not reveal that IRS in integrated vector (pest) management is what Rachel Carson advocated in 1962, nor do they mention that it is also supported by the much larger WHO, several nations in Africa, and the Gates Foundation, all of whom probably do more to fight malaria when they sneeze that AFM does intentionally.

Google and Bing searches turn up no projects the organization actually conducts to provide bed nets, or DDT, or anything else, to anyone working against malaria. I can’t find any place anyone other than AFM describes any activities of the group.

AFM has impressive video ads urging contributions, but the videos fail to mention that nothing in the ad is paid for by AFM, including especially the guy carrying the pesticide sprayer.

Looking at the IRS Form 990s for the organization from 2003 through 2008 (which is organized in both the U.S. and South Africa), it seems to me that the major purpose of AFM is to pay Roger Bate about $100,000 a year for part of the time, and pay Richard Tren more than $80,000 a year for the rest of the time.

Can anyone tell me, what has Africa Fighting Malaria ever done to seriously fight malaria? One could make the argument that if you sent $10 to Nothing But Nets, you’ve saved more lives than the last $1 million invested in AFM, and more to save lives than AFM in its existence.

Tip of the old scrub brush to Pharyngula and Antievolution.org, even though AFM wasn’t what they were targeting.

Update: Tim Lambert at Deltoid sent some traffic this way, which caught the attention of Eli Rabett, which reminded me that there really is more to this story about Africa Fighting Malaria, and you ought to read it at Deltoid and Rabett’s warren.

Formatting issues More (updated September 24, 2013):


Does Africa Fighting Malaria actually fight malaria? (format fix)

June 11, 2010

[Editor’s note: This post is an attempt to fix a formatting error in the earlier post with the almost-same headline, which has some corruption in it I have been unable to find or fix, but which renders the text almost unreadable.  My apologies.  Have not yet figured out how to move comments, alas; check the old post.]

This spring’s publication of a book, The Excellent Powder, by Richard Tren and Donald Roberts, repeating most of the false claims about malaria and DDT, got me wondering. Their organization, Africa Fighting Malaria (AFM):

Does AFM do anything to fight malaria? At its own website it makes some astoundingly grandiose claims:

In its seven years of operation, AFM has helped transform malaria control by taking on and turning around failing public health institutions, donor agencies and governments.

Offhand I can’t think of any public health institution AFM has even been involved with, other than its undeserved criticism of the World Health Organization — and if anyone knows of any donor agency or government AFM has “turned around,” the history books await your telling the story.

Africa Fighting Malaria springs to life every year around World Malaria Day, April 25, with editorials claiming environmentalists have killed millions.  AFM seems to be one of the sources of the bizarre and false claim that Rachel Carson is a “mass murderer.”  AFM makes noise whenever there is difficulty getting a DDT spraying campaign underway in any part of Africa, for any reason, quick to lay the blame on environmentalists, even though the blame generally rests in other places.  AFM is quick on the draw to try to discredit all research into DDT that suggests it poses any health threat, though so far as I can tell AFM has published no counter research, nor has it conducted any research of its own.

In its 2009 Annual Report, AFM proudly states “AFM is the only advocacy group that routinely supports IRS [Indoor Residual Spraying] and through its advocacy work defends the use of DDT for malaria control.”

Cleverly, and tellingly, they do not reveal that IRS in integrated vector (pest) management is what Rachel Carson advocated in 1962, nor do they mention that it is also supported by the much larger WHO, several nations in Africa, and the Gates Foundation, all of whom probably do more to fight malaria when they sneeze that AFM does intentionally.

Google and Bing searches turn up no projects the organization actually conducts to provide bed nets, or DDT, or anything else, to anyone working against malaria.  I can’t find any place anyone other than AFM describes any activities of the group.

AFM has impressive video ads urging contributions, but the videos fail to mention that nothing in the ad is paid for by AFM, including especially the guy carrying the pesticide sprayer.

Looking at the IRS Form 990s for the organization from 2003 through 2008 (which is organized in both the U.S. and South Africa), it seems to me that the major purpose of AFM is to pay Roger Bate about $100,000 a year for part of the time, and pay Richard Tren more than $80,000 a year for the rest of the time.

Can anyone tell me, what has Africa Fighting Malaria ever done to seriously fight malaria?

One could make the argument that if you sent $10 to Nothing But Nets, you’ve saved more lives than the last $1 million invested in AFM, and more to save lives than AFM in its existence.

Tip of the old scrub brush to Pharyngula and Antievolution.org, even though AFM wasn’t what they were targeting.

_____________
Update: Tim Lambert at Deltoid sent some traffic this way, which caught the attention of Eli Rabett, which reminded me that there really is more to this story about Africa Fighting Malaria, and you ought to read it at Deltoid and Rabett’s warren.

More (updated September 24, 2013):


Good news: Warming probably won’t expand malaria much

May 19, 2010

A paper in the May 20 edition of Nature reports that global warming probably won’t expand the range of malaria much.  That’s good news.

Here’s the press release from the University of Florida, touting the paper written by two University of Florida researchers, among others:

Scientists: Malaria control to overcome disease’s spread as climate warms

Filed under Environment, Health, Research on Wednesday, May 19, 2010.

GAINESVILLE, Fla. — Contrary to a widespread assumption, global warming is unlikely to expand the range of malaria because of malaria control, development and other factors that are at work to corral the disease.

So concludes a team of scientists including two University of Florida researchers in a paper set to appear May 20 in the journal Nature.

Scientists and public policy makers have been concerned that warming temperatures would create conditions that would either push malaria into new areas or make it worse in existing ones. But the team of six scientists, including David Smith and Andy Tatem, faculty members with UF’s biology and geography departments and both at UF’s Emerging Pathogens Institute, analyzed a historical contraction of the geographic range and general reduction in the intensity of malaria — a contraction that occurred over a century during which the globe warmed. They determined that if the future trends are like past ones, the contraction is likely to continue under the most likely warming scenarios.

“If we continue to fund malaria control, we can certainly be prepared to counteract the risk that warming could expand the global distribution of malaria,” Smith said.

The team, part of the Wellcome Trust’s multinational Malaria Atlas Project, noted that malaria control efforts over the past century have shrunk the prevalence of the disease from most of the world to a region including Sub-Saharan Africa, Southeast Asia and South America, with the bulk of fatalities confined to Africa. This has occurred despite a global temperature rise of about 1 degree Fahrenheit, on average, during the same period.

“The globe warmed over the past century, but the range of malaria contracted substantially,” Tatem said. “Warming isn’t the only factor that affects malaria.”

The reasons why malaria has shrunk are varied and in some countries mysterious, but they usually include mosquito control efforts, better access to health care, urbanization and economic development. The banned pesticide DDT was instrumental in ridding the disease from 24 countries in Southern Europe, the former Soviet Union and elsewhere in the world between 1955 and 1969, Smith said. Researchers debate how the U.S. defeated malaria, but the reduction of mosquito breeding grounds, improved housing and reduced emphasis on agriculture that comes with development — and the reduced risk of bites that accompanies urbanization – probably played a role, Smith said.

“There is no one tale that seems to determine the story globally,” Tatem said. “If we had to choose one thing, we would guess economic development, but that’s kind of a cop out” because the specific mechanisms may still remain unclear, and controlling malaria might also help to kick-start development.

In any case, current malaria control efforts such as insecticide-treated bed nets, modern low-cost diagnostic kits and new anti-malarial drugs, have proved remarkably effective, with more and more countries achieving control or outright elimination. Unless current control efforts were to suddenly stop, they are likely to counteract the spread of mosquitoes or other malaria-spreading effects from anticipated temperature increases, Smith said.

Simon Hay, an author of the Nature paper and one of the chief architects of the Malaria Atlas Project, noted that modern malaria control efforts “reduce transmission massively and counteract the much smaller effects of rising temperatures.”

“Malaria remains a huge public health problem, and the international community has an unprecedented opportunity to relieve this burden with existing interventions,” he said. “Any failure in meeting this challenge will be very difficult to attribute to climate change.”

Key to controlling malaria is the treatment of the disease in human victims.  Malaria parasites must spend part of their life cycle in humans; if medical care can cure humans, mosquitoes have no well of the disease to draw from, to spread it.

This paper says that global warming won’t spread the disease, so long as medical care and local health officials can keep effective treatments — a complete cure for human victims — coming quickly.

Resources:


Wall Street Journal’s DDT-fueled war on science

May 12, 2010

I don’t subscribe to the Wall Street Journal — their discounts to educators are lousy.

So I missed this editorial when it ran on April 24, 2010 (page A12), “DDT and population control – malaria still kills one million every year.”

Nominally, that should be good news.  At the peak of DDT use in the early 1960s, malaria killed about 3 million people annually.  By the time we banned DDT use on cotton crops in the U.S., the death toll was still about 2 million people annually.  From the heyday of DDT, we’ve decreased malaria’s death toll, to less than half what it was.

Editorial writers at the Journal don’t let facts get in their way when they go off on a misdirected political jihad or crusade.  Gross error Number 1:  They mislead readers about the facts.

They are claiming that a million is too many (it is), but they claim that the total would be significantly less if only Americans would attack Africa with poison.  We have trouble enough with wars in Afghanistan and Iraq, it seems to me.  There is no indication that we could reduce malaria rates with a lot of extra poison.  Malaria is a parasite in human blood.  To defeat the disease we have to defeat the infections in humans.  Mosquitoes just spread the disease from one human to another.  DDT does not cure malaria in humans; it is one preventive device of limited effectiveness.

What are they on about?

The Journal’s editorial writers said:

Environmental activists this week marked the 40th anniversary of Earth Day, which happened to fall three days before World Malaria Day. Insofar as Earth Day politics have contributed to today’s malaria epidemic, the two events are related.

You could see this one coming.  The reactionaries at the editorial seek out opportunities to criticize environmentalists, whose cause they see as anti-business.   The Journal’s editorial page usually carries an op-ed piece by Hoover Institute maven Henry I. Miller about once a year (see here, for example), claiming we need DDT to fight West Nile virus.  We don’t, of course.  West Nile virus-carrying mosquitoes are best fought with other pesticides, when pesticides are used.  They need to be hit before adulthood, while they are still larva, in the water.  DDT is exactly wrong for such applications.  But Miller’s piece comes around almost every year, as soon as the first West Nile virus infections in humans are noted.

So, since they so soundly disregard science on that diatribe, why not here, too?  DDT offers a great target for Tea Baggers, Know-Nothings, and truth bashers.  Most of the history of DDT was written before the internet, so it’s easier to spread falsehoods without contradiction.

Disinformation.  Propaganda.  Shame on the Wall Street Journal.

Earth Day and World Malaria Day are related in this way:  Environmentalists warned us that doing the wrong stuff in the environment would make it harder to fight malaria, and they were right.  People who resist clean air and clean water legislation also resist legislation to stop poisoning our planet.  Those people rarely do anything to fight malaria, either.  Human comfort, human health, human survival, is not what they are concerned about.

Earth Day founder Gaylord Nelson, a U.S. Senator from Wisconsin, was a leading opponent of the insecticide DDT, which remains the cheapest and most effective way to combat malarial mosquitoes.

Gaylord Nelson, the father of Earth Day, was governor of Wisconsin when the University of Wisconsin did the first studies showing that songbirds and raptors in Wisconsin were being wiped out by DDT. We should expect him to be an opponent of indiscriminate use of the stuff.  His state was on the road to ruin, and long before the federal government acted against DDT, Wisconsin had laws and regulations to limit its use.  Wisconsin’s wild populations recovered a bit more quickly because Wisconsin had acted.

Gaylord Nelson at the Apostle Islands, Photograph by Frank Wallick, 1967.

Gaylord Nelson at the Apostle Islands, Photograph by Frank Wallick, 1967.

Nelson also knew that, in the U.S., malaria was conquered by 1939 (according to the Centers for Disease Control).  DDT came along in 1946, seven years later.  While DDT was used to control mosquitoes in the U.S., it was for no disease control reasons — that was why so many people opposed the rather pointless use of the stuff.  And I suspect Nelson was savvy enough to know that DDT has not been the cheapest means of controlling mosquitoes for several years.  One application of DDT in Africa costs about $12.00, for the professional who must apply it, and the testing to determine whether DDT will even work.  One application lasts about six months.  So, for a year’s protection, DDT costs about $24.00 per house, per year.

Bednets cost about $10.00, and last about five years.  That works out to $2.00 year.  For $24.00, you could provide a dozen different nets in a home, though most homes would use them only to protect children.

Moreover, recent test runs in Africa show DDT about 25% to 50% effective in reducing malaria incidence, while bednets are about 50% to 85% effective.  Nets are cheaper and more effective.

Doesn’t the Wall Street Journal have fact checkers?  Or do they just not care about the facts?

Rachel Carson’s 1962 book, “Silent Spring,” misleadingly linked pesticides to cancer and is generally credited with popularizing environmental awareness.

Wrong on three fronts.  Carson noted that the family of chemicals from which DDT comes might have links to cancer, but she did not make the claim that DDT is carcinogenic.  DDT was banned because it’s a long-term, deadly poison that destroys ecosystems.  Cancer in humans was not a part of the equation.

However, DDT is now known to be a weak human carcinogen.  Every cancer-fighting agency on Earth lists it as a “probable human carcinogen” (it is confirmed to cause cancer in other mammals).  Can’t the Wall Street Journal find the phone number of the American Cancer Society?

DDT earned its ban because of 20 years of research data by 1972, showing that DDT kills virtually everything it comes in contact with that is smaller than a large man, and it destroys ecosystems.  Talking about DDT’s carcinogenicity is a red herring.  Carson didn’t claim DDT was a significant cause of cancer, nor was DDT banned from agricultural use because anyone thought it was a significant cause of cancer.  Yes, DDT is a weak human carcinogen, contrary to the Journal’s implication; but no, that’s not why it was banned.

Carson’s book certainly ignited concerns about human activities affecting environment other than land development.  But “environmental awareness” is as old as our nation, at least.  A hundred years prior to Rachel Carson’s book, the U.S. set aside the world’s first National Park, Yellowstone.  60 years earlier, Teddy Roosevelt and Gifford Pinchot led the drive to conserve the nation’s forests.  The Soil Conservation Service, a New Deal program, worked to save soil on farms and unimproved areas, a good 30 years before Carson’s book.  Environmental awareness is an almost-congenital trait in Americans.  Rachel Carson sounded alarms about new reactive chemical combinations.  Americans were already alert to the need to save soil, water, air and wild spaces.

We banned DDT to save our crops and to save our wildlife.  Those are good reasons to keep the ban today.

But other leading greens of the period, including Nelson, biologist Paul Ehrlich and ecologist Garrett Hardin, were also animated by a belief that growth in human populations was harming the environment.

Nelson thought the U.S. needed to slow immigration (see more below).  Ehrlich feared a massive round of starvation, which was staved off only with the Green Revolution and billions of dollars of foreign aid money, the good luck of our having Norman Borlaug and the Rockefeller Foundation, and major economic change in nation’s like India and China.  Hardin pointed out that even the best intentioned people needed a structure to encourage them to conserve, else conservation would not take place.

They all recognized that while any human could minimize her impact on the natural world, no one person could ameliorate all the effects of billions of people.

“The same powerful forces which create the crisis of air pollution also are threatening our freshwater resources, our woods, our wildlife,” said Nelson. “These forces are the rapid increase in population, industrialization, urbanization and scientific technology.”

Notice, please, that Sen. Nelson did not suggest humans should do anything to cause or encourage massive human death (nor did the Journal do the courtesy of noting where they quoted him from).  He merely notes that air pollution and water pollution, and a lack of freshwater, are created by human populations, industry, urban sprawl and technology.  All of these things threaten human health.  Nelson is concerned that we not add to human illness and misery.  That’s not what the Journal’s editorial wants you to think, however.  It will suggest instead that Nelson urged more human suffering and death.

How craven must an editorial board be to accuse good people, falsely, of such sins?

In his book “The Population Bomb,” Mr. Ehrlich criticized DDT for being too effective in reducing death rates and thus contributing to “overpopulation.”

I doubt it.  I can’t find anything quite to that description in my copy of the book.  It’s a common internet legend (one level dumber than urban legend) — but shouldn’t the Wall Street Journal have higher standards than to use for documentation, “my cousin Clem heard a story about a person his aunt once knew?”

Hardin opposed spraying pesticides in the Third World because “every life saved this year in a poor country diminishes the quality of life for subsequent generations.”

Now the Journal is making things up.  In the essay from which the Journal quotes him, Hardin wrote about the dangers of uncontrolled immigration and population growth — almost sounding like an angry Arizona Tea Partier at times — but never did he get close to suggesting that we should not suppress malaria, for any reason.  (Wise readers may wish to see what Hardin actually said, where he really went awry if he did, and how his words resonate today, at his essay, “Living on a Lifeboat.”  Writers at the Journal should be ashamed of savaging the reputation of a guy who is so much in tune with what they usually write.  Notice Hardin does not mention DDT, use of pesticides in foreign nations, malaria, nor any other disease.  He rails at starvation, however.)  When the Wall Street Journal engages in fiction, shouldn’t they let us know?

For these activists, malaria was nature’s way of controlling population growth, and DDT got in the way.

Gee, in context, that’s all fiction. Never did Sen. Gaylord Nelson claim malaria was a good population control tactic, nor that we should stop using DDT to allow more people to die. Those are whole cloth lies. Never did Garrett Hardin say either of those things. Never did Paul Ehrlich say those things.

Cover of 2003 Science Magazine special on Garrett Hardin's essay

Cover of 2003 Science Magazine special on Garrett Hardin’s essay, “Tragedy of the Commons”

For anti-science activists, like the writers at the Wall Street Journal’s editorial page, falsehoods have become coin of the realm, and DDT is just one more sciency thing to try to use as whip against political opponents. The serious question is, why is the Wall Street Journal opposed to clean air and clean water?  Why are they trying to politicize things at all?

The writers at the Journal continue:

Today, malaria still claims about one million lives every year—mostly women and children in sub-Saharan Africa. There’s no evidence that spraying the chemical inside homes in the amounts needed to combat the disease harms humans, animals or the environment. Yet DDT remains severely underutilized in the fight against malaria because the intellectual descendants of Senator Nelson continue to hold sway at the World Health Organization and other United Nations agencies.

Full disclosure would be good here.  Malaria death rates are at the lowest point in history, at least since 1900.  Yes, too many die — but it’s not the fault of “not enough DDT.”  No nation that uses DDT has ever succeeded in eradicating malaria with pesticides alone.  Only those nations that assaulted malaria from the  human side, treating malaria in human victims, have been successful in eradicating the disease.  DDT use was essentially suspended in Africa by the World Health Organization in about 1965, because overuse of DDT in agriculture had bred mosquitoes that are resistant and immune to the stuff.  No amount of DDT spraying, anywhere, can reverse that.  Spraying DDT where mosquitoes are unaffected by it, is stupid.

Plus, studies indicate a correlation between DDT use, even in those small amounts, and premature deaths to children in the households sprayed.  DDT is not harmless.  DDT is not benign.

DDT has never been banned in Africa, and even under the 2001 Persistent Organic Pesticides Treaty (POPs) DDT has a special carve out to keep it available to fight malaria, despite its being a destroyer of worlds.  So implicit in the Journal’s screed here is that Africans are too stupid or lazy to use a substance that would save their children and themselves from malaria, though it’s available relatively cheaply.

Is DDT “underutilized?”  Again we should ask, why would anyone use DDT where it is not effective? Then we should ask, who would use DDT in fighting disease in Africa, and do they use it?  It turns out that DDT is not completely superfluous to all mosquito populations.  But testing is required to be sure DDT will work — were an organization to use ineffective pesticides, thousands could die, and the testing is therefore a preservation of human life.  And, because of past incidents in Africa, for example when DDT killed off the fish local populations depend on for their food, DDT use is extremely limited, to indoor applications only, and only by trained professionals who limit its spread.

WHO has been using DDT in Africa for indoor residual spraying (IRS) since the 1950s.  Use was slowed when DDT’s effectiveness was compromised.  In recent years WHO held a press conference on DDT to encourage locals who fear DDT poisoning to go along, and since 2005 DDT’s effectiveness appears to be dropping.  But DDT is available for use wherever it is needed to fight malaria in Africa.

Is the Wall Street Journal calling for mass poisoning of Africa?  What else could they be talking about?  Why would they call for such a thing?

The Journal claims WHO and other UN agencies are “under the sway” of Sen. Nelson, and that’s bad?  Let’s be clear:  Nelson didn’t oppose use of DDT in Africa to fight malaria.  UN’s WHO is the leading continent-wide advocate of proper use of DDT to fight malaria.  If the Journal claims that current, appropriate use of DDT is too little, what is the Journal advocating?

The good news is that the Obama Administration has continued the Bush policy of supporting DDT spraying in Zambia, Mozambique and other countries where the locals want it used. “Groups like the Pesticide Action Network have lobbied the U.S. Agency for International Development to stop spraying DDT, and Obama is ignoring them so far,” says Richard Tren of Africa Fighting Malaria, an advocacy group. “They’re prioritizing what makes sense from a science and public health point of view.”

Let’s be clear:  The Bush administration refused to allow U.S. money to be used to purchase DDT, or to use DDT, until about 2005.  Environmental Defense, the organization that first sued to stop DDT use in the U.S., argued for years that DDT should be allowed in the limited use WHO proposed, but Bush’s people stood firmly opposed, though never explaining why.  In any African nation where local people want DDT, it’s freely available with other money, of course.  So U.S. opposition, bizarre as it was, was not and is not a barrier to DDT use.

Most environmental groups favor beating malaria, and if a bit of DDT carefully controlled will help do the trick, so much the better.  While business lobbyists have falsely impugned environmentalists for years on this point, actual opposition to DDT use has come, in Uganda for example, from business groups.  Tobacco growers claim they fear some DDT will somehow get on tobacco leaves, and that will make the stuff unsaleable in the European Union.  Cotton growers fear any faint traces of DDT will ruin sales of organic cotton to the EU.  These business groups sued to stop DDT use against malaria in Uganda.

But environmental organizations, like ED, the Sierra Club, and others, have been fighting malaria for 40 years.

Which is more than we can say for Richard Tren.  Tren is one of two or three of the leading false propagandists for poisoning Africa in the world.  He tells false tales about Rachel Carson, false tales about DDT’s harms and effectiveness, and as best I can tell he has never lifted one finger or written one check to fight malaria himself, while taking tens of thousands of dollars to spread his false tales.

There are dozens of noble malaria fighters out there whose opinions we should seek — Socrates Litsios, the late Fred Soper, to mention two.  Why does the formerly august Wall Street Journal use Richard Tren as a source, when there are authoritative people handy to talk?

DDT helped to eradicate malaria in the U.S. and Europe after World War II, and the U.S. is right to take the lead in reforming public health insecticide policy and putting the lives of the world’s poor above green ideology.

Printed in The Wall Street Journal, page A12

According to the history of malaria at the CDC, malaria was essentially wiped out in the U.S. by 1939.  DDT was not available for use for another seven years.  Malaria was gone from northern Europe by World War II.  DDT was a tool in the final eradication of the disease in Italy and Greece.  But the main campaign against malaria was in curing the disease in humans, before the mosquito populations could rise up.

Among the nasty facts of science the Journal either does not know, or refuses to say, DDT can’t eradicate mosquitoes.  In anti-malaria campaigns, DDT is used to knock down the mosquito populations temporarily, so that the disease can be cured in humans.  Mosquito populations will quickly rise again, and in even greater numbers — but if there is no human reservoir of malaria parasites for mosquitoes to draw from, they cannot spread the disease.  Malaria parasites must spend part of their life cycle in humans, and part in mosquitoes.

Curing malaria in humans is the tough part.  It requires money to improve medical care, for accurate and speedy diagnoses, and for prompt and complete treatment of the disease in each patient.  Preventing malaria is aided greatly by better-built homes with screens on windows, the sort of stuff that requires people to have more than subsistence incomes.  So beating malaria generally requires economic development, too.

How much easier is it to bash environmentalists than to confront the real causes of malaria.  Bashing environmentalists won’t do anything to relieve human suffering nor eliminate the disease, so we can bash environmentalists again next World Malaria Day, and next Earth Day — all at no cost to us, safe in our Wall Street Journal offices in Manhattan, New York, U.S.A.  The Journal has fallen victim to bold purveyors of junk and voodoo science, and bogus and voodoo history.  Shame on the Journal.

Curing the disease in humans means the mosquitoes are mere nuisances, and no longer vectors of disease.  Killing the mosquitoes with poison means the disease will be back with a vengeance in a few weeks or months.  Curing humans is more difficult, and more costly — but it saves lives and can save Africa.  We cannot poison Africa to health.

It’s curious, though:  How did they get so poisoned by DDT, up in that office building?

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Quote of the moment: Jonathan Weiner’s Pulitzer-winning explanation of mosquitoes developing immunity to DDT

April 30, 2010

When evolutionists study these worldwide resistance movements, they see four classes of adaptations arising, because an insect under attack has four possible routes to survival.

Jonathan Weiner, author of The Beak of the Finch

Jonathan Weiner, author of The Beak of the Finch, a story of evolution in our time

First, it can simply dodge. Strains of malarial mosquitoes in Africa used to fly into a hut, sting someone, and then land on the hut wall to digest their meals. In the 1950s and 1960s health workers began spraying hut walls with DDT. Unfortunately in every village there were always a few mosquitoes that would fly in through the window, bite, and fly right back out. Millions of mosquitoes died, but these few survived and multiplied. Within a short time almost all of the mosquitoes in the villages were hit-and-run mosquitoes.

Second, if an insect cannot dodge, it can evolve a way to keep the poison from getting under its cuticle. Some diamondback moths, if they land on a leaf that is tainted with pyrethroids, will fly off and leave their poisoned legs behind, an adaptive trick known as “legdrop.”

Third, if the insect can’t keep the poison out, it may evolve an antidote. A mosquito species called Culex pipiens can now survive massive doses of organophosphate insecticides. The mosquitoes actually digest the poison, using a suite of enzymes known as esterases. The genes that make these esterases are known as alleles B1 and B2. Many strains of Culex pipiens now carry as many as 250 copies of the B1 allele and 60 copies of the B2.

Because these genes are virtually identical, letter by letter, from continent to continent, it seems likely that they came from a single lucky mosquito. The mutant, the founder of this particular resistance movement, is thought to have lived in the 1960s, somewhere in Africa or Asia. The genes first appeared in Californian mosquitoes in 1984, in Italian mosquitoes in 1985, and in French mosquitoes in 1986.

Cover of Jonathan Weiner's book, The Beak of the Finch, a story of evolution in our time

Finally, if the insect can’t evolve an antidote,it can sometimes find an internal dodge. The poison has a target somewhere inside the insect’s body. The insect can shrink this target, or move it, or lose it. Of the four types of adaptations, the four survival strategies, this is the hardest for evolution to bring off — but [entomologist Martin] Taylor thinks this is how Heliothis [virescens, a cotton boll-eating moth] is evolving now.

“It always seems amazing to me that evolutionists pay so little attention to this kind of thing,” says Taylor. “And that cotton growers are having to deal with these pests in the very states whose legislatures are so hostile to the theory of evolution. Because it is evolution itself they are struggling against in their fields each season. These people are trying to ban the teaching of evolution while their own cotton crops are failing because of evolution. How can you be a creationist farmer any more?”

Jonathan Weiner, The Beak of the Finch, a story of evolution in our time, Alfred A. Knopf 1994, pp. 254-255. The book won the Pulitzer Prize for general non-fiction in 1995.