A fungus to fight malaria?

February 24, 2011

From a report in The Scientist Daily today:

Researchers have engineered transgenic fungi that drill into mosquitoes and kill the malaria parasite inside — the first tool of its kind — a February 25, 2011 study in Science reported.

Used in conjunction with traditional insecticide methods against mosquitoes, experts say this bioinsecticide has the potential to greatly improve malaria eradication efforts.

Mosquito infected with pathogenic fungus Metarhizium
Image: Courtesy of Raymond St. Leger

“This is a great example of trying to be innovative and use novel ways to look at this problem,” said Matt Thomas, a disease ecologist at Penn State who was not involved in the research. “It’s a move outside the existing insecticide paradigm, which has dominated parasite and vector control for 40-50 years.”

Read more: Fungus fights malaria? – The Scientist – Magazine of the Life Sciences http://www.the-scientist.com/news/display/58028/#ixzz1EuapNz8Z
Difficulties in developing this solution for use in the field promise no quick results.  Testing remains to be done on the process — and then there is the issue of how to infect the proper species of mosquito in the field.  Additionally, since this process involves genetic modification, there will be a raft of government approvals to contend with before deploying it, if it ever is deployed.

Unfortunately, putting the new technique into action may not be an easy task. “There are already difficult challenges in taking forward biopesticide technology,” said Thomas. “Now we’re adding in the additional regulatory and ethical issues around genetically modified organisms. It’s not a hurdle we should just dismiss as unimportant.”

Researchers at several different places pursue very different routes to help ease malaria — not one of them involving an increase in DDT use.
More:
  • Original article in Science:
    W. Fang et al., “Development of Transgenic Fungi That Kill Human Malaria Parasites in Mosquitoes,” Science 311: 1074-77 


Debunking Junk Science’s hoax “100 Things You Should Know About DDT”: #14, William Ruckelshaus’s bias

February 17, 2011

Another in a continuing series, showing the errors in JunkScience.com’s list of “100 things you should know about DDT.” (No, these are not in order.) In the summer of 2009, the denialists have trotted this error out again.

At the astonishingly truthfully-named site “Junk Science,” Steven Milloy creates a series of hoaxes with a page titled “100 things you should know about DDT.”  It is loaded with hoaxes about DDT, urging its use, and about Rachel Carson, and about EPA and the federal regulation of DDT, and about malaria and DDT’s role in the ambitious but ill-fated campaign to eradicate malaria operated by the World Health Organization (WHO) from 1955, officially until 1969.  Milloy knows junk science, and he dishes it out with large ladles.

Among what must be 100 errors, Milloy makes this claim, I suppose to suggest that William Ruckelshaus was biased when Rickelshaus headed the Environmental Protection Agency:

14.  William Ruckelshaus, the administrator of the U.S. Environmental Protection Agency who made the ultimate decision to ban DDT in 1972, was a member of the Environmental Defense Fund. Ruckelshaus solicited donations for EDF on his personal stationery that read “EDF’s scientists blew the whistle on DDT by showing it to be a cancer hazard, and three years later, when the dust had cleared, EDF had won.”

This is a false statement on Milloy’s site.  After finding no credible source for the claim that Ruckelshaus was ever affiliated with EDF in any way, I contacted Ruckelshaus’s office, and got confirmation that Ruckelshaus was not and never has been affiliated with EDF.  It should be a clue that this claim appears only at sites who impugn Ruckelshaus for his action in banning DDT use in U.S. agriculture.

 

Junk Science's oddly apt logo and slogan

Hiding the truth in plain view: Junk Science is a site that promotes junk science, an unintended flash of honesty at a site that otherwise promotes hoaxes about science. Note the slogan. Does this site cover its hoaxes by stating plainly that it promotes “all the junk science that’s fit to debunk?”

It is also highly unlikely that he ever wrote a fund-raising letter for the group, certainly not while he was a public official.  The implicit claim of Junk Science.com, that William Ruckelshaus was not a fair referee in the DDT case, is a false claim.

I asked Milloy to correct errors at his site, and he has steadfastly refused.

Here is what Milloy’s point #14 would say, with the falsehoods removed:

14.  William Ruckelshaus [was] the administrator of the U.S. Environmental Protection Agency who made the ultimate decision to ban DDT in 1972[.], was a member of the Environmental Defense Fund. Ruckelshaus solicited donations for EDF on his personal stationery that read “EDF’s scientists blew the whistle on DDT by showing it to be a cancer hazard, and three years later, when the dust had cleared, EDF had won.”

Below the fold:  William D. Ruckelshaus’s “official” biography, if you call him today, February 17, 2011.  You should note, there is no mention of any work with EDF.

Read the rest of this entry »


USAID policy statement on DDT and malaria control

February 16, 2011

USAID-paid tools and pesticides used to prevent malaria in a campaign coordinated with the government in Tanzania. USAID photo.

USAID-paid tools and pesticides used to prevent malaria in a campaign coordinated with the government in Tanzania. USAID photo.

 

The U.S. Agency for International Development (USAID) issued a statement on their support for the use of DDT, where appropriate.  I don’t have a date — if you know the date, please let me know — but for the record, here’s the statement.

Those who claim the U.S. discourages the use of DDT to the detriment of African and Asians, are incorrect in their claims, once again.

USAID Support for Malaria Control in Countries Using DDT

USAID and Malaria

USAID activities for malaria control are based on a combination of internationally-accepted priority
interventions and country-level assessments for achieving the greatest public health impact, most importantly, the reduction of child mortality (deaths).

Contrary to popular belief, USAID does not “ban” the use of DDT in its malaria control programs. From a purely technical point of view in terms of effective methods of addressing malaria, USAID and others have not seen DDT as a high priority component of malaria programs for practical reasons. In many cases, indoor residual spraying of DDT, or any other insecticide, is not cost effective and is very difficult to maintain. In most countries in Africa where USAID provides support to malaria control programs, it has been judged more cost-effective and appropriate to put US government funds into preventing malaria through insecticide-treated nets, which are every bit as effective in preventing malaria and more feasible in countries that do not have existing, strong indoor spraying programs.

USAID country missions provide support to national malaria control programs in about 21 countries in sub-Saharan Africa, where the burden of malaria deaths is the highest. This support covers a broad range of activities, according to local priorities, resource availability and complementary activities by other donors and multinational institutions in each country.

International efforts to fight malaria are largely coordinated by Roll Back Malaria (RBM), a global partnership that includes leaders from across Africa, African health institutions, the World Health Organization (WHO), UNICEF, World Bank, UNDP, multi-lateral agencies, international, national and local NGOs, and the private sector. USAID is a key RBM partner. RBM has identified three priority interventions to reduce deaths and illness from malaria. These are consistent with USAID ’s priority areas for investment in malaria. These are:

1. Insecticide-Treated Nets (ITNs) for young children and pregnant women.
2. Prompt and Effective Treatment with an anti-malarial drug within 24 hours of onset of fever
3. Intermittent Preventive Therapy (IPT) for pregnant women as a part of the standard ante –
natal services.

Each of these interventions is backed by solid evidence of effectiveness under program conditions and effective in reducing the sickness and death from malaria, especially in Africa. For example, proper use of ITNs can reduce overall child deaths by up to 30% and significantly reduce sickness in children and pregnant women.

DDT in Malaria Programs

DDT is only used for malaria control through the spraying of interior house walls – Indoor Residual Spraying, or (IRS). A number of other insecticides can also be used for IRS, and are in many countries when those alternative insecticides are safer and equally effective. IRS, when efficiently conducted in appropriate settings, is considered to be as efficacious as ITNs in controlling malaria.

In most countries in Africa where USAID provides support to malaria control programs, it has been judged more cost-effective and appropriate to put US government funds into other malaria control activities than IRS. USAID has funded non-IRS support to malaria control programs in countries in which DDT is being used, for example, Eritrea, Zambia, Ethiopia and Madagascar.

USAID regulations (22 CFR 216) require an assessment of potential environmental impacts of supporting either the procurement or use of pesticides in any USAID assisted project, but if the evidence assembled in preparing such an environmental review indicates that DDT is the only effective alternative and it could be used safely such as interior wall spraying undertaken with WHO application protocols, then that option would be considered. The U.S. government is signatory to the Stockholm Convention on Persistent Organic Pollutants (the POPS treaty), which specifically allows an exemption for countries to use DDT for public health use in vector control programs, as long as WHO guidelines are followed and until a safer and equally effective alternative is found. The US voted in favor of this exemption.

There are a few situations in which IRS with DDT is generally found to be appropriate. For example, in South Africa when certain mosquitoes developed resistance to the major alternative class of insecticides, the synthetic pyrethroids, DDT was used. Such situations are relatively rare, however, and demonstrate the value of the provisions of the POPs Treaty, which restrict and document use of DDT, but provide for its use when appropriate.

USAID Interventions

USAID is emphasizing prevention via mosquito nets dipped in pyrethriods – a synthetic insecticide originally found in chrysanthemums. USAID is supporting an innovative Africa regional public-private venture for the commercial distribution of ITNs. In 2003 USAID’s NetMark Project launched insecticide-treated net products in Zambia, Senegal, Ghana, and Nigeria selling more than 600,000 nets and 500,000 insecticide re-treatments during its first five months of operation. In 2004, NetMark will launch in at least five more countries in Africa.

USAID also invests in development of new tools for malaria control, particularly vaccine development and the response to increasing drug resistance. USAID is funding projects to discover and dispense new drugs such as Arteminisin-based combination therapies (ACT), which have proven to be more effective against malaria than the traditional drugs chloroquine and mefloquine. USAID also supports the development of new policies and strategies for use of these new therapies, as well as the improvement of both public and private health systems. Since 1998, the agency has aggressively supported the development of the combination therapy as a safe and effective alternative treatment.  In addition, USAID and its global partners in RBM are working to ensure sustained financing of the drugs. USAID has played a critical role in drawing attention to the spread of drug resistance in Africa and in assisting countries in effectively treating malaria, including the use of combination therapy.

In summary, USAID directs its support for malaria control programs based on evidence for maximum impact on reducing child deaths. Based on this criterion, for most countries with USAID support for malaria control in sub-Saharan Africa, indoor residual spraying (regardless of the choice of insecticide) has not been judged to be the most effective use of US government funds. USAID continues to plan its support for national malaria control programs in sub -Saharan Africa on a country by country basis, and will continue to strive to use US taxpayer funds as efficiently and effectively as possible with the most appropriate tools at our disposal to reduce deaths from malaria.

I suspect that statement is dated.  Here is a site at USAID that details the policy on DDT, malaria and mosquitoes, and includes a different statement under the same title as the above:

USAID and Malaria

USAID activities for malaria control are based on a combination of internationally accepted priority interventions and country-level assessments for achieving the greatest public health impact, most importantly, the reduction of child mortality (deaths).

USAID backs a comprehensive approach to prevent and treat malaria. This includes:

  • Spraying with insecticides (“indoor residual spraying,” or IRS) in communities: IRS is the organized, timely spraying of an insecticide on the inside walls of houses or dwellings. It is designed to interrupt malaria transmission by killing adult female mosquitoes when they enter houses and rest on the walls after feeding, but before they can transmit the infection to another person. IRS has been used for decades and has helped eliminate malaria from many areas of the world, particularly where the mosquitoes are indoor-resting and where malaria is seasonally transmitted. USAID and the President’s Malaria Initiative (PMI) activities include conducting environmental assessments, training spray teams, procuring insecticide and equipment, and developing and evaluating spraying activities.
  • Insecticide-treated mosquito nets (ITNs): Bednets treated with insecticide have been proved highly effective in killing mosquitoes. In addition, the netting acts as a protective barrier.  Consistently sleeping under an ITN can decrease severe malaria by 45 percent, reduce premature births by 42 percent, and cut all-cause child mortality by 17 to 63 percent. PMI is expanding access to free and highly subsidized nets while also creating commercial markets in African countries.
  • Lifesaving drugs: Artemisinin-based combination therapies (ACTs) are the most effective and rapidly acting drugs currently available for treating malaria.  PMI activities include purchasing ACT drugs; setting up management and logistics systems for their distribution through the public and private sectors; and training health care workers and community caregivers in their use.
  • Intermittent preventive treatment for pregnant women (IPTp): Each year, more than 30 million African women living in malaria-endemic areas become pregnant and are at risk for malaria. IPTp involves the administration of at least two doses of sulfadoxine-pyrimethamine (SP) to a pregnant woman through antenatal care services.  The treatment helps to protect pregnant women against maternal anemia and low birthweight, which contributes to between 100,000 and 200,000 infant deaths annually in Africa.  PMI activities include purchasing SP, training health care workers in administering the drug, and providing information about IPTp to pregnant women.

USAID and DDT

USAID supports indoor residual spraying (IRS) with DDT as an effective malaria prevention strategy in tropical Africa in those specific situations where it is judged to be the best insecticide for IRS both epidemiologically and entomologically and based on host-country policy. Its use for IRS to prevent malaria is an allowable exception under the Stockholm Convention – also known as the Persistent Organic Pollutants Treaty or POPs Treaty – when used in accordance with WHO guidelines and when safe, effective, and affordable alternatives are not available. For a variety of reasons, some countries do not conduct IRS or have not registered DDT for use in their malaria control programs.  The reasons may include the epidemiological situation of the country, the organizational capacity of the program, or in some cases, concerns related to their agricultural export market.  The Stockholm Convention aims to eventually end the use of all POPs, including DDT.

The determination of which of the WHO-approved insecticides to use for USAID’s IRS programs is made in coordination with the host-country malaria control program, with the primary objective of preventing as many malaria infections and deaths as possible.  That determination is based on cost-effectiveness; on entomological factors; on local building materials; and on host-country policy.  USAID adheres to strict environmental guidelines, approval processes, and procedures for the use of DDT and all other WHO-approved insecticides in its malaria control programs. As part of our environmental assessments and safer use action plans, we help countries build capacity for safe and judicious use of all chemicals used in their malaria control programs, including DDT

The fact is that DDT is more effective and less expensive than many other insecticides in many situations; as a result, it is a very competitive choice for IRS programs.   DDT specifically has an advantage over other insecticides when long persistence is needed on porous surfaces, such as unpainted mud walls, which are found in many African communities, particularly in rural or semi-urban areas.

USAID has never had a “policy” as such either “for” or “against” DDT for IRS.  The real change in the past two years has been a new interest and emphasis on the use of IRS in general – with DDT or any other insecticide – as an effective malaria prevention strategy in tropical Africa.  (Recent successful applications of IRS, particularly in the southern Africa region, have also contributed to the keen interest among donors and among African malaria control programs.)  For example, in Fiscal Year 2005, USAID supported less than $1 million of IRS in Africa, with programs utilizing insecticides purchased by the host government or another donor.  For fiscal year 2007, in the PMI and in other bilateral programs, USAID will support over $20 million in IRS programs in Africa, including the direct purchase of insecticides.  This dramatic increase in the scale of our IRS programs overall is the greatest factor in DDT’s recent prominence in USAID programs.

USAID Issue Briefs

President’s Malaria Initiative (PMI)

Tanks of pesticide (DDT?) used for Indoor Residual Spraying (IRS) against malaria in Africa bear the labels to indicate USAID paid for the tools and the pesticide, contrary to hoaxsters' claims.

Tanks of pesticide (DDT?) used for Indoor Residual Spraying (IRS) against malaria in Africa bear the labels to indicate USAID paid for the tools and the pesticide, contrary to hoaxsters’ claims.

Update: If you’re here from a religious discussion group that veered off into malaria and DDT, you’d do well to use this site’s search feature, and search for DDT.  Most of the statements from those favoring DDT in your discussion are pure, buncombe, junk science, as this site and several others reveal.


No, DDT is not the easy answer to malaria

February 13, 2011

Roger Bate and Richard Tren, the Dynamic Duo of DDT, have been busy lately.  Bate appears to have found additional funding from the radical right-wing American Enterprise Institute, where I gather he has been prowling the halls trying to sell others there on the idea that DDT is an easy solution to malaria, and only mad, despotic environmentalist megalomaniacs have stopped DDT from saving Africa from malaria, the American economy from depression, and Major League Baseball from the designated hitter rule.  (I thought it odd that his bio doesn’t mention his work for tobacco interests as integral to his organizing.)

Graphic from a 1950s-era ad for DDT

Graphic from a 1950s-era ad for DDT. No, it's not right -- it's Madison Avenue then, expressing the claims of the "DDT-is-good-for-you" hoaxsters of today.

I don’t exaggerate much, if at all.

So, I’ll bore you with rebuttals over the space of the next few days.  Especially among the right-wing echo chambers, comments are frequently moderated to oblivion when they are allowed at all.

For example, there is a site that calls itself Minnesota Prager Discussion Group — a site for Dennis Prager groupies.  Here’s a post that may have been prompted by a Dennis Prager broadcast, but which cites a scurrilous pamphlet written by Bates and Tren, with Donald Roberts, carrying all sorts of calumny against environmentalists, health care professionals, diplomats, environmentalists and scientists — cloaked in a high degree of disrespect for readers who, they hope, have never bothered to read Rachel Carson and have forgotten everything they may have ever read about DDT and environmental harms it causes.

Here’s the post on DDT and malaria there:

Malaria Can Be Easily Controlled by DDT

Posted on February 2, 2011 by Glenn H. Ray

DDT Still Critical in Fight against Insect-Borne Diseases

Through a mix of environmental fervor, self-interest and disregard for evidence-based policy, United Nations (UN) agencies are misleading the public about the insecticide DDT — mistakenly claiming it is not needed and can be eliminated globally by 2020, says Donald Roberts, emeritus professor of tropical medicine at Uniformed Services University of the Health Sciences, Roger Bate, the Legatum Fellow in Global Prosperity at the American Enterprise Institute, and Richard Tren, the executive director of Africa Fighting Malaria.

  • UN agencies are misleading the public by claiming that malaria can be controlled without insecticides, notably DDT; the stated aim is to stop DDT use globally by 2020.
  • UN agencies are committing scientific fraud by deliberately and incorrectly interpreting data on malaria control using noninsecticide methods.

While DDT is no panacea, it is still a critical weapon in the battle against malaria and other insect-borne diseases, say Roberts, Bate and Tren.

Source: Roger Bate, Donald Roberts and Richard Tren, “The United Nations’ Scientific Fraud against DDT,” American Enterprise Institute, January 21, 2011.

Above information came from the National Center of Policy Analysis

Dennis Prager regularly reminds his listeners that many tens of thousands of lives can be saved by approving DDT uses in certain areas in Africa.

Oy.  Helluva lotta error and deception packed in a couple hundred words.

So, I tried to help the “discussion group” get to some more accurate understanding of DDT and malaria.

Ed Darrell, on February 2, 2011 at 4:53 pm said:

1. There is no shortage of DDT.

2. Not only is DDT not a panacea, it is increasingly not effective against malaria-carrying mosquitoes.

3. Richard Tren leads an astro-turf organization that collects hundreds of thousands of dollars, but does very little if anything to actually fight malaria. These sorts of diatribes increase contributions to his organization’s coffers, but they don’t help fight malaria.

4. In actual practice over the last decade, bednets have proven to reduce malaria by 50% to 85% in areas where they are deployed; DDT is only 25% to 50% effective.

5. Bednets cost about $10 and last about five years — $2.00 per year. DDT costs upwards of $12 per application, and must be applied twice per year — $24.00 per year. Bednets stop mosquitoes cold. DDT depends on mosquitoes biting people first, then resting on a DDT-coated wall — and we hope that it’s a young mosquito that has not yet contracted malaria itself and is not shedding the parasites.

6. Malaria deaths, worldwide, are lower now than at any other time in human history. Since the U.S. stopped using DDT on cotton in 1972, the death rate to malaria has been cut in half. The death toll to malaria is, today, less than 25% of what it was when DDT use was at its peak. Statistically, it appears that cutting DDT use also cuts malaria.

7. We know that’s not the case, but those statistics prove that we can beat malaria without DDT — as indeed, the U.S. Army beat malaria without DDT to build the Panama Canal by 1915, 24 years before DDT was discovered to have any insecticidal properties. In the U.S., with the great aid of the Tennessee Valley Authority, malaria was essentially wiped out by 1939 — seven years before DDT became available for use against mosquitoes. No nation relying on DDT has been able to eradicate malaria.

Roger Bate, Donald Roberts and Richard Tren commit health care terrorism when they tell their fraud-laced stories against the UN and the health care professionals who fight malaria. Shame on them.

Did the author read anything I wrote?  He responded, politely for a guy who didn’t quite get it:

Glenn H. Ray, on February 9, 2011 at 12:19 pm said:

Ed Darrell: Thank you very much for this information.

Let us assume every item you mention is accepted beyond debate..

Malaria still ravages populations in Africa. We are not beating malaria without DDT.

Dennis Prager agrees with you regarding the value of bed nets and from his visits to Africa, has encouraged financial support to increase their availability.

The question still remains, why is DDT still banned rather than being available for use where needed?

My responses:

Sometimes the facts stare us in the face and we can’t see them.

You said:

Malaria still ravages populations in Africa. We are not beating malaria without DDT.

We have cut malaria 75% from when DDT was heavily used. We are beating malaria as best we can since DDT advocates overused DDT and made it ineffective against most populations of mosquitoes. (WHO’s program to eradicate malaria was effectively ended in 1965 because overuse of DDT by large agricultural interests had bred mosquitoes resistant to and immune to DDT; today, every mosquito on Earth carries the alleles that make them resistant and immune to DDT.)
It doesn’t matter how much we whine about DDT being “banned,” DDT doesn’t work to beat malaria now, and it was never intended to be more than a very temporary solution while medical care, treating the humans, did the real work.

When we beat malaria (as in the U.S.), the fact that humans do not have the disease means that mosquitoes cannot catch it from humans. That means the mosquito bites go back to being annoyances, and we don’t need to worry about them.

Malaria is a disease of humans. If we concentrate on the mosquitoes, we can reduce it, temporarily. If we concentrate on treating the disease, and preventing the disease in humans, we can forget about mosquitoes.

Dennis Prager agrees with you regarding the value of bed nets and from his visits to Africa, has encouraged financial support to increase their availability.

Then why is he talking smack against them? He’s talking untruths about DDT, untruths carried by the anti-bednet lobby, like the so-called “Africa Fighting Malaria” lobbying group. Bednets are twice to almost four times as effective as DDT, if they are used exclusive of each other. You don’t get that impression from Prager. Bednets cost a fraction of what DDT treatments cost. Bednets are effective longer than DDT treatments.

We can beat malaria without DDT. We can’t beat malaria without bednets. If he has no truck against bednets, Prager should get out of the bed of the anti-bednet, pro-DDT lobby, and talk about beating malaria.

The question still remains, why is DDT still banned rather than being available for use where needed?

No, the question is, why aren’t you listening?

DDT is not banned anywhere in Africa, and never has been. DDT is freely available to any government who wishes to use it — or private groups who wish to use it.

DDT doesn’t work as it once did, plus, it’s a deadly poison to fish, amphibians, reptiles, birds and small mammals. DDT is unsafe in use outside of Indoor Residual Spraying, where it is increasingly less effective — and Africans are nervous about IRS because their children keep getting sick with strange new diseases even when the kids are safe from malaria. There may be no solid connection between the new syndromes and DDT, but since DDT is not a panacea, not as effective as untreated bednets, and much less effective than treated bednets — why take a chance?

Opposition to DDT today comes from Dennis Prager’s and AFM’s friends in business in Africa. The only serious opposition to DDT I’ve found in Africa was in Uganda, where businessmen sued to stop spraying two years ago.

What in the world makes you think there isn’t all the DDT out there that health workers need?

Any discussion of fighting malaria that involves DDT takes away from the serious fight to beat malaria. A lot of westerners think DDT is a magic potion, and that if we just poison the hell out of Africa with the stuff, we can beat malaria without serious effort, without serious research, without improving the lives of the poor people of Africa who are victimized by the disease.

We beat malaria in the U.S. by improving housing, beefing up public health services, and increasing incomes of families of victims. It took 20 years of concentrated work — all before DDT was even discovered to kill bugs.

To beat malaria in Africa, we must improve housing, beef up medical care, both diagnoses and treatment of the disease, and improve the lives of the families of victims to prevent new disease-causing bites.

It’s tough work. Prager appears not to have the stomach for it. If so, he should say so, instead of claiming, falsely, that DDT could do the job.

Malaria proves a tough foe, difficult to beat. DDT could play a very small role in the defeat of malaria, but more DDT won’t help, and malaria isn’t winning because DDT isn’t available. DDT is readily available. DDT doesn’t work anymore, and DDT was never intended to be a sole weapon.

And:

Lancet recently devoted most of an issue to fighting malaria, and how to beat it. Lancet is perhaps the world’s leading medical journal, certainly among the top three, with no axe to grind, and concerned with improving the condition of humans throughout the world — from a medical care perspective.

The articles come from the world’s leading malaria fighters and those in the vanguard of research on how to beat malaria.

Here’s the executive summary (8 pages in .pdf form).

Did you notice? No call for DDT.

Can you and Dennis Prager please get on board with the campaign to beat malaria? Howling about false, junk science claims that DDT should be used to poison Africa isn’t a ticket to get on that malaria-fighting train.

Mr. Ray responded again:

Thank you again for your interaction. It has been my understanding that many of the claims about the toxicity of DDT to the living groups you have listed has been exaggerated, particularly in regard to the bird populations.
As you might note, malaria control is not my field of expertise, but I have read this claim from two sources over the past decade, but I cannot refer you to them.
I shall remember your ‘corrections’ in any discussion I might have in the future about DDT.

I am certain Dennis has no connections with any businesses in Africa dealing with DDT.

Denial among people who admit that they don’t know much about the topic is really quite amazing, isn’t it?

I made one more comment, but Ray has held it in his site’s moderation queu for enough days I am convinced he plans to leave it there.  Here is what I posted that he has not yet let through:

Ed Darrell, on February 10, 2011 at 12:49 am said: Your comment is awaiting moderation.

Thank you again for your interaction. It has been my understanding that many of the claims about the toxicity of DDT to the living groups you have listed has been exaggerated, particularly in regard to the bird populations.

Peer review research over the past 40 years has borne out the early research from 1945 through 1961 that showed DDT is a killer of birds, reptiles, fish, amphibians and small mammals. I am unaware of any study anywhere that denies this toxicity, except with regard to insects who produce new generations quickly enough to evolve resistance and immunity.

Discover magazine looked for studies saying DDT doesn’t harm larger animals, but found none. In November 2007 the magazine noted:

In fact, Carson may have underestimated the impact of DDT on birds, says Michael Fry, an avian toxicologist and director of the American Bird Conservancy’s pesticides and birds program. She was not aware that DDT—or rather its metabolite, DDE—causes eggshell thinning because the data were not published until the late 1960s and early 1970s. It was eggshell thinning that devastated fish-eating birds and birds of prey, says Fry, and this effect is well documented in a report (pdf) on DDT published in 2002 by the Department of Health and Human Services’ Agency for Toxic Substances and Disease Registry (ATSDR). The report, which cites over 1,000 references, also describes how DDT and its breakdown products accumulate in the tissues of animals high up on terrestrial and aquatic food chains—a process that induced reproductive and neurological defects in birds and fish.

DDT kills birds outright, through acute poisoning. That was what first sounded the alarms at Michigan State University, the University of Wisconsin, and a dozen other places across the U.S. DDT accumulates in fat tissues, and poisons the brains of migrating birds when they are under stress during migration. DDT poisons chicks of birds in the eggs, killing them outright, or making them unable to feed after hatching. DDT makes female birds unable to lay competent eggs (thins the eggshells), which means even if the chick is free of the toxins, the egg can’t protect it through incubation. DDT scrambles the sex organs of birds, making hermaphrodites, and making both genders unable to mate successfully.

Most of these death mechanisms apply in other species, too. The saving grace for humans is that we are so large. DDT doses required for much of this documented damage is much higher than we get. Still, in humans, modest amounts of DDT mimic estrogen, producing premature onset of menses in little girls, and swollen mammaries and shrunken testes in boys.

There are several studies that indicate the carcinogenic effects of DDT are weak in humans. Those studies frequently are touted as having “proven DDT harmless.” Not at all. They only show that DDT isn’t as bad as tobacco in causing cancers. That’s not an endorsement of health.

As you might note, malaria control is not my field of expertise, but I have read this claim from two sources over the past decade, but I cannot refer you to them.

Any source you have will trace back to the junk science promulgated by Steven Milloy, a former henchman of the tobacco lobby, and Gordon Edwards, a formerly respected entomologist who appears to have gone off the deep end with an obsession against Rachel Carson. Neither ever published any research to back up their claims. Edwards is dead, and Milloy is a long-time political propagandist — you won’t see any research from them.

Search Pub-Med. Check the ornithology and wildlife journals. Under U.S. law, were DDT not a deadly toxin, EPA could not ban it. DDT manufacturers sued EPA to overturn the ban, and they lost twice. The courts agree that the evidence against DDT is more than sufficient for regulation of the stuff as EPA did.

I shall remember your ‘corrections’ in any discussion I might have in the future about DDT.

Thank you. Feel free to check my blog, Millard Fillmore’s Bathtub, for further developments on malaria.

The hoax case for DDT, and against Rachel Carson, the UN, the World Health Organization and all of science and medical care, is getting a significant set of boosts from Tren, Bate and Roberts this winter.  Let us hope, if only for the sake of truth and accuracy, that their stuff doesn’t get any more traction than it already has.

Other recent postings on DDT and malaria and policy


Annals of Hoaxes: American Enterprise Institute sends out hoax backgrounder on DDT and trade barriers

January 25, 2011

How do hoaxes get started?

The self-proclaimed august American Enterprise Institute issued a “backgrounder” today on foreign trade.  Backgrounder #2509, written by James Roberts.

The first paragraph is complete fiction:

Decades ago, the use of DDT (dichlorodiphenyltrichloroethane) was banned worldwide for what were generally seen as noble and unassailable environmental and public health reasons. Today, ample evidence shows that the ban on DDT spraying has been a tragic mistake. In developing countries, it is linked to millions of preventable deaths from malaria. Worse, some protectionist European business sectors and activist groups continue to exploit the fears of DDT in ways that increase the suffering of the poor around the world.

Here are the errors of fact:

  1. DDT has never been banned worldwide, so there could never be a decades-old worldwide ban. A nearly-world-wide ban was agreed upon by treaty  in late 2001, less than one decade ago.  However, any nation may ignore the ban, legally, by simply writing a letter to the World Health Organization (WHO) saying the nation will be using DDT.  DDT manufacturing continues in a few nations today, including North Korea and India.  India is far and away the largest user of DDT now, using more than all other nations combined.  No worldwide ban on DDT ever existed, and DDT use has been continuous since 1946.
  2. Earlier bans on DDT were assailed in court as unreasonable infringements on commerce. The U.S. banned DDT use on agricultural crops in 1972, but only after two federal district courts had ruled the substance essentially uncontrollable in the wild, and after a lengthy administrative law hearing at the Environmental Protection Agency (EPA) covering most of 1971 and more than 9,000 pages of testimony.  EPA’s rule left DDT available in the U.S. for emergency use, or for health use.  EPA’s rule left manufacturing alone so the U.S. could export DDT to any other nation who wanted to use it.  Still, DDT manufacturers fought hard in court to overturn the ruling.  Manufacturers argued that the science was thin to back the ban, and that the ban was too much regulation for small gain.  Appeals courts ruled that the science backing the ban was ample.
  3. 39 years after the U.S. ban on crop spraying with DDT, benefits are enormous — history and science show the recovery of dozens of beneficial species, ranging from mosquito-eating Mexican free-tail bats in Texas, through fish in Oklahoma, to osprey, peregrine falcons, brown pelicans and bald eagles in the rest of the U.S. Unknown at the time EPA acted, DDT has been shown to be an endocrine disruptor of the sort that scrambles the sex organs of fish and amphibians in the Potomac and Susquehanna Rivers in the U.S.  Also unknown in 1972, EPA now is listed by the American Cancer Society as a “probable human carcinogen,” though it is thought to be a weak carcinogen to adults directly exposed.
  4. Malaria deaths have been cut by 75% since DDT was indicted as a harmful substance. Perhaps more surprising, without DDT, health workers around the world have sharply reduced malaria incidence and especially malaria deaths.  Nearly four million people died from malaria, worldwide, at the height of DDT use in 1959 through 1961.  Today that death toll has been cut to under 900,000, through wise use of curative pharmaceuticals, careful use of prophylactic nets and home improvements, and the development of new, better-targeted pesticides.  Malaria fighters especially are redoubling efforts to make the disease at least rare, now encouraged by the dramatic strides made without relying on DDT.  Ironically, India has a growing malaria problem, despite its being the greatest user of DDT today.  (Even more ironic:  Roberts claims about half the death rate WHO does — a 90% reduction in malaria deaths.)
  5. No preventable death to malaria has been tied to a lack of DDT. No nation has ever had difficulty getting DDT if it wanted it.  The fight against malaria was hampered when the malaria parasites developed resistance to traditional pharmaceuticals used to treat the disease in humans, but the promulgation of artemisinin-based combination therapies made up the gap. Nations have difficulty developing a health care system that can quickly and accurately diagnose malaria, and which form of malaria, and then deliver the necessary therapeutic regimen of pharmaceuticals to cure humans.  DDT cannot make up for that difficulty, partly because DDT use itself now requires rather extensive testing to make sure it works.  As Jonathan Weiner noted in his Pulitzer Prize-winning The Beak of the Finch, nearly every mosquito on Earth today carries at least one of two alleles which make them resistant or wholly immune to DDT.  DDT cannot be used without first testing to be sure the mosquitoes are killed by it.
  6. No otherwise noble European or “western” business groups nor environmental groups work against the minor use of DDT for indoor residual spraying (IRS). For example, the Environmental Defense Fund was one of the groups that lobbied the Bush administration to allow USAID money to buy DDT for IRS in Africa, a use the Bush administration inexplicably had not allowed.  Opposition to this minor DDT use in Uganda was organized by Uganda businessmen who sued to stop it, not by European groups — generally.  BAT, British-American Tobacco, did organize opposition to use of DDT, on specious grounds — highly ironic since the people who run the pro-DDT publicity machine are, several of them, former tobacco propagandists whose organizations go seed money from tobacco companies.  Generally, DDT use for IRS in Africa is supported by everyone involved, including environmentalists and the U.S. government.

Four sentences and six grievous errors of fact from the American Enterprise Institute.  And this is just the first paragraph of their “background” paper.

James Roberts may have tried to pluck an example from a history he does not understand.  There may be a problems with trade and pharmaceuticals and pesticides — but none of the problems he cites for DDT is accurate and true.  He may have fallen for the hoaxes perpetrated by others.

Watch:  A hundred others will cite the hoax conclusions Roberts lists, claiming American Enterprise Institute as the source.  Likely they will assume AEI had its facts straight, and wasn’t the victim of a hoax.

And that’s how hoaxes get started, big time. This is how no-think tanks wage the War on Science.

Will AEI issue a correction?

Does anyone take such publications as authoritative?  May God forbid.

With such a sloppy start, can the rest of the paper be any better?

(Oy, now I scan down the document, and I see Roberts cited Rachel Carson’s Silent Spring as saying DDT use would lead to extinction of birds, “offering no proof.”  Since Carson made no such direct claim, and since the book was loaded with citations to the studies that proved her points, that is it was loaded with “proof,” we must conclude that Roberts did not bother to actually open the book, let alone read it.  That doesn’t speak well for the chances of getting a correction.)


George Clooney’s malaria? DDT didn’t cure it

January 25, 2011

Not sure why, but pro-DDT sites have been harping about George Clooney’s having contracted malaria, a second time, while performing one of his humanitarian acts in southern Sudan.

George Clooney in Sudan, Time Magazine photo

George Clooney in Sudan, Time Magazine photo

True, Clooney got malaria.  His take?

“This illustrates how with proper medication, the most lethal condition in Africa can be reduced to bad ten days instead of a death sentence.”

Sometimes it may pay to remember that malaria is disease caused by a parasite who must live part of its life cycle in humans, and part of its life in mosquitoes.  Killing mosquitoes only works until the next susceptible mosquito comes along to bite an infected human.

The goal of malaria prevention and eradication campaigns generally is to cure the humans, so regardless how many mosquitoes may be in a given location and regardless how many people they may bite, there is no malaria pool for the mosquitoes to draw from, to spread to other humans.

To beat malaria, we need to prevent the spread of the disease.  At some point that requires providing quick and accurate diagnoses of which parasites cause the infection, and a complete and completed regimen of therapeutic pharmaceuticals to actuall cure the human victims.  DDT is mostly a bystander in that crucial part of the fight.

What was Clooney doing in Sudan?  According to the New York Daily News:

Clooney was in Sudan in December to work with Google and the UN on a human rights project that combines satellite imagery analysis and field reports to prevent a new war from occurring in the troubled country.

“We want to let potential perpetrators of genocide and other war crimes know that we’re watching, the world is watching,” he said in a statement at the time. “War criminals thrive in the dark. It’s a lot harder to commit mass atrocities in the glare of the media spotlight.”

Do you consider it odd that Clooney’s contracting malaria might gather more news in western outlets than his actual trip to Sudan, to call attention to the campaign against genocide?

World Blog – The race to contain drug-resistant malaria

January 23, 2011

NBC News’s World Blog carried a series on malaria and fighting it around the world.  Here’s part I:

PAILIN, Cambodia – The border crossing between Thailand and Cambodia at Pailin has a rather bleak feel about it at the best of times. In the heavy monsoon rain, the dingy checkpoints are reduced to gray smudges.

Vodpod videos no longer available.

World Blog – The race to contain drug-resistant…, posted with vodpod

 

See more video information from NBC, here.


Roger Bate’s simple lie about DDT

January 22, 2011

In the last two weeks we’ve seen a virtual-world assault by Richard Tren, Roger Bate and Don Roberts, alternately telling fantastic tales about how Rachel Carson from beyond the grave organized a mass murder that rivals Joseph Stalin, or saying that environmentalists conspire to keep life-saving chemicals from getting to Africa and Asia.

This morning’s e-mail brought a release from the often-fact-challenged American Enterprise Institute, under the by-line of Roger Bate — “The UN’s Scientific Fraud Against DDT.”

Fraud?  That’s all on Bate.  Here are things Bate will not tell you:

  • No malaria fighting organization claims it needs more DDT.
  • DDT has never been banned in Africa, nor Asia.
  • If any nation wishes to use DDT to fight malaria, that nation need only write a letter to the World Health Organization informing WHO of that fact.
  • If anyone violates the Persistent Organic Pollutants Treaty (POPs) and uses DDT without telling WHO first, there is no penalty.
  • Malaria death rates are, now, at the lowest level in human history.  While there is a threat of a resurgence of malaria, the threat comes because the malaria parasites themselves develop resistant to the pharmaceuticals used to treat the disease in humans — no connection to DDT.
  • DDT use cannot stop malaria.  Consider:  India is one of two or three nations today who still manufacture DDT, and India uses more DDT than all the rest of the world’s nations put together.  Malaria is still a problem for India.
  • Beating malaria requires more than poisoning the hell out of Africa.

Roger Bate:  Walking science, history, law and policy fraud.  His claims are hoaxes.

Update: Tim Lambert at Deltoid looked at the claims of Bate and Roberts, and found that they appear to have made many errors in simple math and statistics.  Read about it here.


EPA at 40: Director Jackson claims too much?

December 18, 2010

EPA turned 40 on December 2.* EPA Director Lisa Jackson somehow wangled a few inches from the Wall Street Journal’s opinion page to extol the virtues of the agency.

She’s come under fire from some quarters, including especially the Home for Unwed Crabs,  for overstating the case.  Did she?

EPA Director Lisa P. Jackson

EPA Director Lisa P. Jackson

Or is this one more case of using environmentalists as scapegoats by the hard right, and other know-nothings and know-not-enoughs?

Jackson’s piece makes mild defense of a great idea in government, I think.  To me, the critics appear hysterical in comparison.

In tracking this down, I discovered that Matt Ridley had been given some really bum information about Rachel Carson, DDT and malaria, which appears in his new book, The Rational Optimist. To his credit, Ridley made a quick correction of the grossest distortions.  He defends the premises, still, however, which I find troubling. There may be subject for a later comment.

Disinformation is insidious.  Claims against the accuracy and reputation of Rachel Carson follow the stories of Millard Fillmore’s bathtub, but with darker, malignant intent.

Seriously:  What does Lisa Jackson overstate here?

The EPA Turns 40

‘Job-killing’ environmental standards help employ more than 1.5 million people.

Forty years ago today, the U.S. Environmental Protection Agency opened its doors, beginning a history of improvements to our health and environment. We reach this milestone exactly one month after the midterm elections strengthened the influence of groups and individuals who threaten to roll back the EPA’s efforts.

Last month’s elections were not a vote for dirtier air or more pollution in our water. No one was sent to Congress with a mandate to increase health threats to our children or return us to the era before the EPA’s existence when, for example, nearly every meal in America contained elements of pesticides linked to nerve damage, cancer and sometimes death. In Los Angeles, smog-thick air was a daily fact of life, while in New York 21,000 tons of toxic waste awaited discovery beneath the small community of Love Canal. Six months before the EPA’s creation, flames erupted from pollution coating the surface of Cleveland’s Cuyahoga River, nearly reaching high enough to destroy two rail bridges.

These are issues that are above politics. The last 40 years have seen hard-won advances supported by both sides of the aisle, and today the EPA plays an essential role in our everyday lives. When you turn on the shower or make a cup of coffee, the water you use is protected from industrial pollution and untreated sewage. In fact, drinking water in Cleveland was recently shown to be cleaner than a premium brand of bottled water. You can drive your car or catch a bus without breathing dangerous lead pollution. At lunch, would you prefer your food with more, or less, protection from pesticides?

The most common arguments against these protections are economic, especially as we continue to recover from the worst downturn since the Great Depression. Fortunately, the last 40 years show no evidence that environmental protection hinders economic growth. Neither the recent crisis nor any other period of economic turmoil was caused by environmental protection. In fact, a clean environment strengthens our economy.

Special interests have spent millions of dollars making the case that we must choose the economy or the environment, attacking everything from removing lead in gasoline to cleaning up acid rain. They have consistently exaggerated the cost and scope of EPA actions, and in 40 years their predictions have not come true.

We have seen GDP grow by 207% since 1970, and America remains the proud home of storied companies that continue to create opportunities. Instead of cutting productivity, we’ve cut pollution while the number of American cars, buildings and power plants has increased. Alleged “job-killing” regulations have, according to the Commerce Department, sparked a homegrown environmental protection industry that employs more than 1.5 million Americans.

Even in these challenging times, the EPA has been part of the solution, using Recovery Act investments in water infrastructure, clean-diesel innovation and other projects to create jobs and prepare communities for more growth in the years ahead.

The EPA’s efforts thrive on American ingenuity and entrepreneurship. Holding polluters accountable sparks innovations like the Engelhard Corporation’s catalytic converter, which pioneered the reduction of toxic emissions from internal combustion engines, and DuPont’s replacements for chlorofluorocarbons (CFCs), which protected the ozone layer while turning a profit for the company. One executive told me that the EPA’s recent standards for greenhouse gas emissions from cars will help create hundreds of jobs in a state where his company operates—a state whose U.S. senators have both opposed the EPA’s authority to regulate greenhouse gases.

These attacks are aimed at the EPA, but their impacts are felt by all Americans. Pollutants like mercury, smog and soot are neurotoxins and killers that cause developmental problems and asthma in kids, and heart attacks in adults. We will not strengthen our economy by exposing our communities and our workers to more pollution.

In these politically charged times, we urge Congress and the American people to focus on results from common-sense policies, not inaccurate doomsday speculations. That is how we can confront our nation’s economic and environmental challenges and lay a foundation for the next 40 years and beyond.

Ms. Jackson is administrator of the Environmental Protection Agency.

* [Oops. Same birthday as Donna. Happy birthday, Donna! Happy EPA’s 40th (yours, too? can’t be much more, can it?)]


Mandy Moore Talks Mosquito Nets – ABC News

December 13, 2010

Don’t ask me what work she’s done, because I couldn’t tell you.  I can tell — based on the headlines of the clipping services — that Mandy Moore is popular.

Ironically, in her brief tour of Africa and — shall we label it? — probably-shallow understanding of the issues, Ms. Moore has a deeper understanding of malaria and how to fight it than the most erudite of the DDT denialists, like Michael Crichton, or Rutledge Taylor.  Innocence wins.

For ABC News, the actress talked about charity work in Africa:

Vodpod videos no longer available.

Mandy Moore Talks Mosquito Nets – ABC News, posted with vodpod

It’s a case of a celebrity doing “Do a Good Deed” duty, most likely.  In the video, Mandy Moore puts DDT denialists to shame.  In writing?  Moore doesn’t come off as well.  (Did she write that piece herself?  Maybe she should write what she talks.)


BBC News – Malaria ‘cannot be eradicated’

November 29, 2010

BBC report: Experts say control, not eradication of malaria (short advertisement precedes news video):

Vodpod videos no longer available.

BBC News – Malaria ‘cannot be eradicated’, posted with vodpod

More, and resources:

Lancet map, showing nations where  malaria eradication may be possible, and those where control may be the best solution

Map from The Lancet, accompanying article: "Malaria is caused by five species of a parasite that can be carried from human to human by mosquitoes. Over the last 150 years, the portion of the world where malaria is still endemic has shrunk, but the disease is still endemic in 99 countries. However 32 of these countries, most of them on the edges of the endemic zone, are attempting to eradicate the disease, while the rest are trying to reduce infections and deaths though control measures."


Delingpole: Wrong and bitter on DDT

November 21, 2010

The Daily Telegraph’s James Delingpole got suckered by the anti-Rachel Carson propaganda, and wrote a bitter piece complaining about how environmentalists are ruining the environment and people’s lives (double whammy:  environmentalists worry about people over profits, and the environment over corporations, so Delingpole hoped to tweak ’em at both ends).  Lots of discussion, too much to read and most of it nasty and off target.

It was a smaller part of Delingpole’s generally anti-science, contrary-to-fact rant about global warming.

Chris Goodall fixed all of Delingpole’s errors on DDT at Carbon Commentary.

Being pro-DDT has become as religious an exercise as being for creationism taught in public schools.  There’s no good evidence to support the point, but there are a tiny handful of people who are gullible enough to spread whatever they say.  That tiny handful of advocates never gets the facts on their side, nor they on the side of the facts, but they appear deluded enough that they get their panties in a wad if you point out that their claims are false.  “I’m not a liar!” they’ll retort with indignation good enough to make them rivals of the Portugal soccer squad’s acting, or just crazy enough to fail to recognize their errors.

And so the falsehoods spiral on virally.

Rachel Carson’s ghost should get busier.  DDT can’t stop malaria, and now rarely slows it at all.  Rachel Carson was right — and had we listened in 1962, malaria might be a lot less prevalent today.


Lancet special issue on malaria eradication: No call for more DDT

October 30, 2010

Lancet is one of the premiere research journals in the world for all of science, but especially for issues of health and medicine.

Image from Lancet illustrating malaria story

Image from Lancet –
Mother and child under a mosquito bite-preventing bednet.

On October 29, 2010, Lancet published a special report, “Malaria Elimination.”  Much science.  Much history.  No call for more DDT.

A plan for research is laid out.  Plans to eradicate malaria from more than 90 nations are laid out, explained and debated.  Calls for more research are made.  Calls for disciplined action from nations and health care organizations, and donor organizations.

But no call for more DDT.

Go take a look at the issue.  Several of the articles are available for no charge, out from behind the usual Lancet paywall.

Get the real science, real history, real policy.  Environmentalists are not evil villains there.  malaria is the villain in that story, and serious health care researchers and deliverers discuss serious methods to beat the disease.  Consequently, DDT has only a bit part.

Resources:


Called this one right: DDT advocates think poison is always the answer

October 25, 2010

This is a story about the persistence of bad information, and about the flow of news and other new information.

At about the same time I was writing about the Lancet study on potential undercounting of malaria deaths in India, Debora McKenzie at New Scientist pored over the same article (maybe the same Bloomberg News piece), and reported it in greater detail than I did here.  McKenzie’s piece is worthy of a read.

Glenn Reynolds, Instapundit

Glenn Reynolds, Instapundit

Glenn Reynolds at Instapundit picked up on McKenzie’s piece — but reflecting his pro-poison and anti-humanitarianism bias, he tacked on a gratuitous slap at health workers, scientists and governments who tried to eradicate malaria in the 20th century:

MALARIA KILLING MORE PEOPLE THAN WE THOUGHT?

Malaria has always been one of humanity’s biggest killers, but it may be far bigger than we realised. An unprecedented survey of the disease suggests that it kills between 125,000 and 277,000 people per year in India alone. In contrast, the World Health Organization puts India’s toll at just 16,000.

Other countries using similar accounting methods, such as Indonesia, may also be underestimating deaths from malaria. That means it could be killing many more than the WHO’s official estimate of nearly 1 million people a year worldwide, suggesting more money should be spent to fight it.

It’s too bad the malaria eradication efforts were allowed to fail.

“Allowed” to fail?  Reynolds assumes someone wanted the program to fail?  Reynolds assumes someone could have stopped the failure, other than the pro-DDT forces who overused the stuff and drove mosquitoes to evolve resistance, or other than the governments of Subsaharan Africa who could not mount massive health care campaigns due to the instability of their governments?  It’s too bad the program failed — it was mighty ambitious.  “Allowed to fail” is an undeserved slap at malaria fighters like Fred Soper.

This slip to finger-pointing is what I warned about in my post:  Though India is the world’s greatest manufacturer of DDT, and though more DDT is used in India today than the rest of the world combined, someone will look at the undercount story, blame the imaginary ban on DDT, blame Rachel Carson (who never advocated a ban on DDT), and make some smug political snark.

Reynolds was pulled away from the snark, fortunately.  Reader Kevin O’Brien wrote to Reynolds about  the difficulties of beating any disease, using smallpox as his launching point.  Beating smallpox was a massive effort, made easier by the fact that the pox resided only in humans, as opposed to the malaria parasite’s two-species life cycle.  O’Brien’s missive to Reynolds, a few errors included, is the best commentary Reynolds has had on DDT and disease in some time.

One frequently-obnoxious blogger pulled back from the brink is not enough, though.

Andrew Bolt

Andrew Bolt

Andrew Bolt jumped the shark at his blog for the Melbourne (Australia) Daily Sun.  The headline for his post is inflammatory and wrong, and warns us that most of what Bolt writes will be wrong:

How many children did Carson’s green lies kill?

Foolish hope that DDT could be a magic bullet against malaria, like Bolt’s,  helps frustrate workable plans to fight the disease.  Policy makers being convinced that some political conspiracy keeps DDT from working to beat malaria, in effect kills children.  Fighting malaria requires long, hard work, to bolster health care systems in entire nations, to accurately and quickly diagnose malaria, and to provide complete treatment to cure human victims.  That work is hampered by policy makers and popular opinion who hold that DDT would be cheaper and quicker, and effective.  Bolt takes any source, no matter how scurrilous, in his unholy condemnation of conservationists and scientists, especially Rachel Carson.  His sole source to condemn Carson is a publication from the far, far-fringe.

How many children will Bolt’s brown lies kill? one could ask.

I warned earlier:

Watch.  Advocates of poisoning Africa and Asia will claim scientists and environmental activists are somehow to blame for any underreporting, and they will call for more DDT use, claiming a ban has made India a refuge for malaria.  Those reports will fail to mention India’s heavy DDT use already, nor will they suggest an ineffectiveness of the nearly-sacred powder.

Andrew Bolt, you’ve made me a prophet — a saddened and disappointed prophet.  It’s good to see Glenn Reynolds step back from the brink of hysteria.  It’s too bad Bolt took the plunge.  Others will probably follow Bolt.

How far will the bad claims spread?


“3 billion and counting” — the errors one makes when using Howard Stern as a science advisor

October 7, 2010

“3 Billion and Counting” premiered at a tiny New York venue a couple of weeks ago, the latest skirmish in the War on Science. Physician-to-the-stars Dr. Rutledge Taylor claims that malaria could be eradicated if only DDT had not been banned from Africa.

What?  No, no, you’re right: DDT has never been banned from Africa, not even under the 2001 Persistent Organic Pollutants Treaty.  The film comes out of Hollywood, starring a Hollywood physician.  Perhaps that should clue us in that it is not a serious documentary, and not to be taken at face value.

Nor at any value.

Taylor engaged a publicist and conducted a national campaign to launch the movie.  In that campaign he someone appeared on Howard Stern’s radio show.  [There’s a guy in comments who claims it wasn’t Taylor, though Taylor wrote it in the first person.  Odd as hell.]

How silly are the claims in the movie?

A post at the movie’s blog revealed that Ronnie, Stern’s limousine driver, had a fight with bedbugs, and that Stern thinks DDT should be brought back.  That’s how bad this movie is:  Howard Stern is the science advisor.

Yes, yes, you’re right:  DDT stopped working against bedbugs in the 1950s (see Bug Girl’s recent post).  That doesn’t stop the publicists from defending the movie at the movie’s blog.  “Royce” [who claims not to be a publicist for the movie] said:

The problem with DDT is that it worked too well in stomping out malaria. The science proves that it minimally impacted the environment. But this information was suppressed. Wonder why and by whom? This movies addresses and uncovers the answers to these questions..Questions that many of us had about this issue.

I tried, without success I’m sure, to set him straight:

Royce,

First, DDT was not the weapon that eradicated malaria in the U.S.  We worked for 30 years to improve medical care, beef up the Public Health Service and county public health officers, educate people on how to drain mosquito breeding areas near their homes, be certain people with malari were fully treated to a cure, and to raise incomes to improve housing so that people could live in a home where mosquitoes could not enter at night (the times malaria-carrying mosquitoes bite).  By 1939, malaria was essentially eliminated from the U.S.  DDT was not available for use for another seven years.

Earlier we had defeated malaria and yellow fever in Panama, during the construction of the Panama Canal — long before any insecticide existed.  Beating malaria is possible with discipline, accurate information, and sustained effort.  No pesticide is necessary.

Second, DDT has never been out of use in Africa since 1946, nor in Asia.  DDT is in use right now by the World Health Organization (WHO) and at least five nations in Africa who have malaria problems.  If someone told you DDT is not being used, they erred.

Unfortunately, overuse of DDT by agricultural interests, in the early 1960s, bred mosquitoes that are resitant and immune to DDT.  DDT simply is not the effective pesticide it once was, and for the WHO project to eradicate malaria, this problem was the death knell.  WHO had to fall back to a malaria control position, because pro-DDT groups sprayed far too much of the stuff, in far to many places, mostly outside.

Third, all serious studies indicate that DDT greatly affects environment, with doses of the stuff multiplying from application through the top of the trophic levels in the ecosystem.  A minimal dose of DDT to kill mosquito larva in an estuary, for example, multiples many times as zooplankton and the mosquito larva soak it up.  The next level of consumers get about a ten-times dose from what was sprayed, and that multiplies exponentially as other creatures consume the lower-level consumers.  By the time an insect or crustacean-eating bird gets the critter, the dose is millions of times stronger, often to fatal levels for the bird.

If the dose is sub-lethal, it screws up the reproduction of the bird.  DDT in the egg kills the chick before it can fledge from the nest, often before it can hatch.  If by some miracle the chick does not die from acute DDT poisoning, the eggshells produced by a DDT-tainted female bird are often too thin to survive the growth of the embryo — either way the chicks die.  (There are a couple of studies done on plant-eating birds which showed that the chicks did not die before hatching — they died shortly after hatching.)

DDT is astoundingly effective at screwing up the reproduction of birds.

Fourth, studies show that humans exposed to DDT rarely get an acutely toxic dose, but that their children get screwed up reproductive systems, and there is a definite link from DDT exposure to the children of the mother — the cancer goes to the next generation.  DDT is not harmless to people at all — it is just not acutely toxic, generally.

Fifth, as I note above, DDT is no longer highly effective in controlling mosquitoes.  Where once it killed them dead, they have developed immunity, and now digest the stuff as if it were food.  There are studies that show DDT is also weakly repellent, but there are better, less-toxic repellents, and there is no reason to use something so deadly to all other creatures in the ecosystem to get a weak repellent effect.

Because of the biomagnification, DDT kills the predators of mosquitoes much more effectively, and for a much longer period, than it kills mosquitoes.  This sets the stage for mosquitoes to come roaring back, with all the natural checks on mosquito population out of commission.

Why use a poison that is not very effective, but very deadly, when there are better alternatives available?

Malaria death rates are the lowest they have been in human history.  There is no good case to be made that more DDT could provide any benefit.

DDT is still manufactured in astonishing quantity in North Korea, for one.  DDT is used in Africa and Asia, but no one with any sense uses it to eradicate malaria — DDT screwed up that chance 50 years ago.

Rutledge’s movie appears to be sinking from release (it’s played two theaters that I can find, for less than a week at each).  It may be far underwater already.  It would be to DDT whatExpelled” was to creationism, but it lacks the cloying, gullible religious fanatics to push it.

Thank God.

Malaria-fighting pesticide sprayers in Africa - publicity still from "3 Billion and Counting"

Mystery photo: If spraying pesticides to fight malaria isn't allowed in Africa as Rutledge Taylor argues, why are these pesticide sprayers pictured in this photo? Publicity still from "3 Billion and Counting" via Rotten Tomatoes website

Also see, at Millard Fillmore’s Bathtub: